Polysaccharides from exudate gums of plants and interactions with the intestinal microbiota: A review of vegetal biopolymers and prediction of their prebiotic potential.

Autor: Silva FCO; Department of Biochemistry, Biotechnology Laboratory (LaBioTec), Federal University of Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235 - University City, CEP 50.670-901 Recife, PE, Brazil., Malaisamy A; Transcription Regulation Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi 110067, India., Cahú TB; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro (UFRJ), University City, CEP 21941-913 Rio de Janeiro, RJ, Brazil., de Araújo MIF; Department of Biochemistry, Biotechnology Laboratory (LaBioTec), Federal University of Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235 - University City, CEP 50.670-901 Recife, PE, Brazil., Soares PAG; Department of Biochemistry, Biotechnology Laboratory (LaBioTec), Federal University of Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235 - University City, CEP 50.670-901 Recife, PE, Brazil., Vieira AT; Department of Biochemistry and Immunology, Laboratory of Microbiota and Immunomodulation (LMI), Federal University of Minas Gerais (UFMG), Antonio Carlos, 6627 - Pampulha, CEP 30.161-970 Belo Horizonte, MG, Brazil., Dos Santos Correia MT; Department of Biochemistry, Glycoprotein Laboratory (BIOPROT), Federal University of Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235 - University City, CEP 50.670-901 Recife, PE, Brazil. Electronic address: maria.tscorreia@ufpe.br.
Jazyk: angličtina
Zdroj: International journal of biological macromolecules [Int J Biol Macromol] 2024 Jan; Vol. 254 (Pt 2), pp. 127715. Date of Electronic Publication: 2023 Nov 02.
DOI: 10.1016/j.ijbiomac.2023.127715
Abstrakt: Polysaccharides in plant-exuded gums are complex biopolymers consisting of a wide range of structural variability (linkages, monosaccharide composition, substituents, conformation, chain length and branching). The structural features of polysaccharides confer the ability to be exploited in different industrial sectors and applications involving biological systems. Moreover, these characteristics are attributed to a direct relationship in the process of polysaccharide enzymatic degradation by the fermentative action in the gut microbiota, through intrinsic interactions connecting bacterial metabolism and the production of various metabolites that are associated with regulatory effects on the host homeostasis system. Molecular docking analysis between bacterial target proteins and arabinogalactan-type polysaccharide obtained from gum arabic allowed the identification of intermolecular interactions provided bacterial enzymatic mechanism for the degradation of several arabinogalactan monosaccharide chains, as a model for the study and prediction of potential fermentable polysaccharide. This review discusses the main structural characteristics of polysaccharides from exudate gums of plants and their interactions with the intestinal microbiota.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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