[Early predictor of bronchial suture failure after pneumonectomy].

Autor:	Porkhanov VA; Research Institution - Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russia.; Kuban State Medical University, Krasnodar, Russia., Zhikharev VA; Research Institution - Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russia.; Kuban State Medical University, Krasnodar, Russia., Bushuev AS; Research Institution - Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russia., Zima VS; Research Institution - Ochapovsky Regional Clinic Hospital No. 1, Krasnodar, Russia., Koryachkin VA; St. Petersburg State Pediatric Medical University, St. Petersburg, Russia., Ivanova MP; Astana Medical University, Astana, Republic of Kazakhstan.
Jazyk:	ruština
Zdroj:	Khirurgiia [Khirurgiia (Mosk)] 2023 (10), pp. 71-77.
DOI:	10.17116/hirurgia202310171
Abstrakt:	Objective: To identify the relationship between serum CRP/albumin and bronchial suture failure after pneumonectomy. Material and Methods: A retrospective analysis included 100 patients who underwent pneumonectomy with extended lymph node dissection for lung cancer. Patients were divided into 2 groups depending on postoperative complications: group 1 - bronchial stump failure, group 2 - no similar complications. In all patients, we analyzed markers of inflammation (C-reactive protein and albumin) in preoperative period and after 24 postoperative hours. Bronchial stump failure was found in 20 patients (10 patients (14.7%) after left-sided pneumonectomy and 10 (31%) patients after right-sided pneumonectomy). We found a significant relationship between serum CRP/albumin and bronchial stump failure after pneumonectomy ( p <0.05). A prognostic formula was based on the ratio of serum C-reactive protein and albumin: PC = CRP/Alb, where PC - prognostic coefficient, CRP - serum C-reactive protein (mg/l) 24 hours after surgery, Alb - serum albumin (g/l) 24 hours after surgery. PC >2.6 determines high risk of bronchial stump failure after pneumonectomy, PC <2.6 - low risk. Sensitivity of this method is 90%, specificity - 97.5%.
Databáze:	MEDLINE
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