| Autor: |
Borenstein JT; Bioengineering Division, Draper, Cambridge MA 02139, USA. jborenstein@draper.com., Cummins G; School of Engineering, University of Birmingham, Edgbaston, B15 2TT, UK. G.Cummins@bham.ac.uk., Dutta A; Department of Electrical & Computer Engineering, University of Connecticut, USA. abhishek.dutta@uconn.edu., Hamad E; Biomedical Engineering Department, School of Applied Medical Sciences, German Jordanian University, Amman, Jordan. Eyad.Hamad@gju.edu.jo., Hughes MP; Department of Biomedical Engineering, Khalifa University, Abu Dhabi, United Arab Emirates. Michael.hughes@ku.ac.ae., Jiang X; Department of Biomedical Engineering, Southern University of Science and Technology, China. jiang@sustech.edu.cn., Lee HH; Weldon School of Biomedical Engineering, Center for Implantable Devices, Purdue University, West Lafayette, IN, USA. hwlee@purdue.edu., Lei KF; Chang Gung University, Taiwan. kflei@mail.cgu.edu.tw., Tang XS; University of Waterloo, Waterloo, ON N2L 3G1, Canada. tangxw@uwaterloo.ca., Zheng Y; Nanyang Technological University, Singapore. YJZHENG@ntu.edu.sg., Chen J; Department of Electrical and Computer Engineering, University of Alberta, Edmonton, AB T6G 2R3, Canada. jchen@ece.ualberta.ca. |
| Abstrakt: |
The development of micro- and nanotechnology for biomedical applications has defined the cutting edge of medical technology for over three decades, as advancements in fabrication technology developed originally in the semiconductor industry have been applied to solving ever-more complex problems in medicine and biology. These technologies are ideally suited to interfacing with life sciences, since they are on the scale lengths as cells (microns) and biomacromolecules (nanometers). In this paper, we review the state of the art in bionanotechnology and bioMEMS (collectively BNM), including developments and challenges in the areas of BNM, such as microfluidic organ-on-chip devices, oral drug delivery, emerging technologies for managing infectious diseases, 3D printed microfluidic devices, AC electrokinetics, flexible MEMS devices, implantable microdevices, paper-based microfluidic platforms for cellular analysis, and wearable sensors for point-of-care testing. |
