Magnetic layered double hydroxides with carbamazepine for breast cancer treatment.
Autor: | Peralta MF; Centro de Investigación y Tecnología Química (CITeQ), UTN-CONICET, Av. Cruz Roja Argentina y Maestro López, Córdoba, 5000, Argentina., Mendieta SN; Centro de Investigación y Tecnología Química (CITeQ), UTN-CONICET, Av. Cruz Roja Argentina y Maestro López, Córdoba, 5000, Argentina., Scolari IR; Unidad de Investigación y Desarrollo en Tecnología Farmacéutica (UNITEFA), UNC-CONICET, Departamento de Ciencias Farmacéuticas, Universidad Nacional de Córdoba, Av. Medina Allende S/N, Córdoba, 5000, Argentina., Gerbaldo MV; Centro de Investigación y Tecnología Química (CITeQ), UTN-CONICET, Av. Cruz Roja Argentina y Maestro López, Córdoba, 5000, Argentina., Oliva MI; Instituto de Física Enrique Gaviola (IFEG), UNC-CONICET, Facultad de Matemática, Astronomía, Física y Computación, UNC, Av. Medina Allende S/N, Córdoba, 5000, Argentina., Gil GA; Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC), UNC-CONICET, Av. Haya de la Torre S/N, Córdoba, 5000, Argentina., Granero GE; Unidad de Investigación y Desarrollo en Tecnología Farmacéutica (UNITEFA), UNC-CONICET, Departamento de Ciencias Farmacéuticas, Universidad Nacional de Córdoba, Av. Medina Allende S/N, Córdoba, 5000, Argentina., Crivello ME; Centro de Investigación y Tecnología Química (CITeQ), UTN-CONICET, Av. Cruz Roja Argentina y Maestro López, Córdoba, 5000, Argentina. |
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Jazyk: | angličtina |
Zdroj: | Heliyon [Heliyon] 2023 Oct 14; Vol. 9 (10), pp. e21030. Date of Electronic Publication: 2023 Oct 14 (Print Publication: 2023). |
DOI: | 10.1016/j.heliyon.2023.e21030 |
Abstrakt: | Current cancer chemotherapy is associated with many side effects and, in some cases, drug resistance, which makes the search for new active molecules and drug delivery strategies imperative. Carbamazepine is an antiepileptic compound that has shown efficacy against breast cancer cell lines. In this study, it was incorporated into layered double hydroxide nanoclays, the percentage of drug loading was increased compared to previous research, and the clays were impregnated with magnetic Fe Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2023 The Authors.) |
Databáze: | MEDLINE |
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