Unlocking the Anticancer Potential of Frankincense Essential Oils (FEOs) Through Nanotechnology: A Review.

Autor: Al-Balushi RA; Department of Basic and Applied Sciences, College of Applied and Health Sciences, A'Sharqiyah University, P.O. Box 42, Ibra, 400, Sultanate of Oman. rayya.albalushi@asu.edu.om., Haque A; Department of Chemistry, College of Science, University of Hail, Hail, Kingdom of Saudi Arabia. a.haque@uoh.edu.sa., Saeed M; Department of Biology, College of Science, University of Hail, Hail, Kingdom of Saudi Arabia., Al-Harthy T; Department of Basic and Applied Sciences, College of Applied and Health Sciences, A'Sharqiyah University, P.O. Box 42, Ibra, 400, Sultanate of Oman., Al-Hinaai M; Department of Basic and Applied Sciences, College of Applied and Health Sciences, A'Sharqiyah University, P.O. Box 42, Ibra, 400, Sultanate of Oman., Al-Hashmi S; Department of Basic and Applied Sciences, College of Applied and Health Sciences, A'Sharqiyah University, P.O. Box 42, Ibra, 400, Sultanate of Oman.
Jazyk: angličtina
Zdroj: Molecular biotechnology [Mol Biotechnol] 2024 Nov; Vol. 66 (11), pp. 3013-3024. Date of Electronic Publication: 2023 Nov 01.
DOI: 10.1007/s12033-023-00918-5
Abstrakt: Cancer is a group of heterogeneous diseases that occur when cells in the body proliferate and divide uncontrollably. As the current treatment modalities have pros and cons, the discovery of new chemotherapeutic agents with the least side effects is one of the most investigated research areas. In this context, plant-based natural products are a rich source of drugs and have served humanity for ages. Frankincense essential oils (FEOs) are among the most promising plant-based oils in Gulf countries. In addition to their high cultural value, FEOs are also famous for their engaging biological activities, including anti-cancerous. However, the practical application of FEOs is often hindered/by their low water solubility, limited bioavailability, high volatility, and sensitivity toward heat, humidity, light, or oxygen. Thus, a significant demand for technological advancement would improve their ability to target particular cells and tissues. Nanotechnology emerged as an exciting approach in this context. Through suitable nano-formulation (functionalization or encapsulation into a nanostructure), issues arising due to solubility, targeting capability, and delivery can be controlled.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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