Environmental Conditions as Determinants of Kidney Stone Formation.

Autor: González-Enguita C; Hospital Universitario Fundación Jiménez Díaz, Avenida Reyes Católicos, 2, 28040 Madrid, Spain., Bueno-Serrano G; Hospital Universitario Fundación Jiménez Díaz, Avenida Reyes Católicos, 2, 28040 Madrid, Spain., López de Alda-González A; Hospital Don Benito, Avenida Primero de Mayo, 25, 06400 Don Benito, Badajoz, Spain., García-Giménez R; Departamento de Geología y Geoquímica, Facultad de Ciencias, Universidad Autónoma, 28049 Madrid, Spain.
Jazyk: angličtina
Zdroj: ACS applied bio materials [ACS Appl Bio Mater] 2023 Nov 20; Vol. 6 (11), pp. 5030-5036. Date of Electronic Publication: 2023 Nov 01.
DOI: 10.1021/acsabm.3c00722
Abstrakt: Urolithiasis is a disease characterized by the presence of stones in the urinary tract, whether in the kidneys, ureters, or bladder. Its origin is multiple, and causes can be cited as hereditary, environmental, dietary, anatomical, metabolic, or infectious factors. A kidney stone is a biomaterial that originates inside the urinary tract, following the principles of crystalline growth, and in most cases, it cannot be eliminated naturally. In this work, 40 calculi from the Don Benito, Badajoz University Hospital are studied and compared with those collected in Madrid to establish differences between both populations with the same pathology and located in very different geographical areas. Analysis by cathodoluminescence offers information on the low crystallinity of the phases and their hydration states, as well as the importance of the bonds with the Ca cation in all of the structures, which, in turn, is related to environmental and social factors of different population groups such as a high intake of proteins, medications, bacterial factors, or possible contamination with greenhouse gases, among other factors.
Databáze: MEDLINE