Severe Hypercalcemia due to Hypervitaminosis D in a Breastfed Infant.
| Autor: | Barzilay JR; Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Pediatrics, Boston Medical Center, Boston, MA 02119, USA., Kreienkamp RJ; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Gordon RJ; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. |
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| Jazyk: | angličtina |
| Zdroj: | JCEM case reports [JCEM Case Rep] 2023 May 17; Vol. 1 (3), pp. luad049. Date of Electronic Publication: 2023 May 17 (Print Publication: 2023). |
| DOI: | 10.1210/jcemcr/luad049 |
| Abstrakt: | Vitamin D is one of the most commonly recommended dietary supplements and is often the first medication ever prescribed in infancy. However, with the variety of concentrations available, including many over-the-counter formulations, dosing errors can easily occur. We present a case of a breastfed infant with a calcium level greater than 23 mg/dL (5.75 mmol/L), whose severe hypercalcemia was due to hypervitaminosis D from accidentally overdosed vitamin D supplementation. We consider the differential diagnosis for her presentation and review the interventions required for treatment of her hypercalcemia. Notably, we reinforce the importance of carefully reviewing dosing of vitamin D supplementation with families. We also discuss the management of hypercalcemia, including the role of fluids, diuretics, and glucocorticoids, as well as the long-term sequalae of severe hypercalcemia. (© The Author(s) 2023. Published by Oxford University Press on behalf of the Endocrine Society.) |
| Databáze: | MEDLINE |
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