Metastatic Merkel Cell Carcinoma Within a Cortisol-producing Adrenal Adenoma.
| Autor: | Cutrone L; Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Subauste J; Department of Specialty Services, G.V. (Sonny) Montgomery Veteran Affairs Medical Center, Jackson, MS 39216, USA., Gomez-Sanchez C; Department of Specialty Services, G.V. (Sonny) Montgomery Veteran Affairs Medical Center, Jackson, MS 39216, USA., Joiner S; Department of Specialty Services, G.V. (Sonny) Montgomery Veteran Affairs Medical Center, Jackson, MS 39216, USA. |
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| Jazyk: | angličtina |
| Zdroj: | JCEM case reports [JCEM Case Rep] 2023 Sep 20; Vol. 1 (5), pp. luad100. Date of Electronic Publication: 2023 Sep 20 (Print Publication: 2023). |
| DOI: | 10.1210/jcemcr/luad100 |
| Abstrakt: | A 54-year-old man with hypertension, type 2 diabetes mellitus, and a history of Merkel cell carcinoma (MCC) of the right thigh presented to the emergency department with a 4-day history of right lower-quadrant abdominal pain associated with constipation and decreased appetite. Workup showed a heterogenous 6-cm right adrenal mass with macroscopic fat. Imaging was suggestive of benign pathology. Hormonal workup for the adrenal nodule led to the diagnosis of Cushing syndrome. The patient underwent a right adrenalectomy for Cushing syndrome with pathology revealing a 6.5-cm adrenocortical adenoma harboring a 2-cm, well-circumscribed neuroendocrine tumor consistent with metastatic MCC. Adrenal collision tumors are exceedingly rare. This case describes a collision tumor that has not previously been identified-a cortisol-producing adrenal adenoma and metastatic MCC. (Published by Oxford University Press on behalf of the Endocrine Society 2023.) |
| Databáze: | MEDLINE |
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