Autobiographical Cerebral Network Activation in Older Adults Before and After Reminiscence Therapy: A Preliminary Report.

Autor:	Viard A; INSERM, U1077, EPHE, Université de Caen Normandie, PSL Research University, GIP Cyceron, CHU de Caen, Neuropsychologie et Imagerie de la Mémoire Humaine (NIMH), Caen, France., Allen AP; Trinity College Institute of Neuroscience (TCIN), Trinity College Dublin, Dublin, Ireland.; Department of Psychology, Maynooth University, Maynooth, Ireland., Doyle CM; Department of Psychology, Maynooth University, Maynooth, Ireland., Naveau M; UNICAEN, CNRS, CEA, INSERM, UAR3408 CYCERON, Normandie University, Caen, France., Bokde ALW; Trinity College Institute of Neuroscience (TCIN), Trinity College Dublin, Dublin, Ireland., Platel H; INSERM, U1077, EPHE, Université de Caen Normandie, PSL Research University, GIP Cyceron, CHU de Caen, Neuropsychologie et Imagerie de la Mémoire Humaine (NIMH), Caen, France., Eustache F; INSERM, U1077, EPHE, Université de Caen Normandie, PSL Research University, GIP Cyceron, CHU de Caen, Neuropsychologie et Imagerie de la Mémoire Humaine (NIMH), Caen, France., Commins S; Department of Psychology, Maynooth University, Maynooth, Ireland., Roche RAP; Department of Psychology, Maynooth University, Maynooth, Ireland.
Jazyk:	angličtina
Zdroj:	Biological research for nursing [Biol Res Nurs] 2024 Apr; Vol. 26 (2), pp. 257-269. Date of Electronic Publication: 2023 Oct 31.
DOI:	10.1177/10998004231210982
Abstrakt:	Introduction: Reminiscence therapy (RT), which engages individuals to evoke positive memories, has been shown to be effective in improving psychological well-being in older adults suffering from PTSD, depression, and anxiety. However, its impact on brain function has yet to be determined. This paper presents functional magnetic resonance imaging (fMRI) data to describe changes in autobiographical memory networks (AMN) in community-dwelling older adults. Methods: This pilot study used a within-subject design to measure changes in AMN activation in 11 older adults who underwent 6 weeks of RT. In the scanner, participants retrieved autobiographical memories which were either recent or remote, rehearsed or unrehearsed. Participants also underwent a clinical interview to assess changes in memory, quality of life, mental health, and affect. Findings: Compared to pretreatment, anxiety decreased (z = -2.014, p = .040) and activated significant areas within the AMN, including bilateral medial prefrontal cortex, left precuneus, right occipital cortex, and left anterior hippocampus. Conclusion: Although RT had subtle effects on psychological function in this sample with no evidence of impairments, including depression at baseline, the fMRI data support current thinking of the effect RT has on the AMN. Increased activation of right posterior hippocampus following RT is compatible with the Multiple Trace Theory Theory (Nadel & Moscovitch, 1997). Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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