Cardiac surgery-Associated acute kidney injury - A narrative review.

Autor:	Rasmussen SB; Department of Anaesthesiology and Intensive Care, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Boyko Y; Department of Anaesthesiology and Intensive Care, Odense University Hospital, Odense, Denmark., Ranucci M; Department of Cardiovascular Anaesthesiology and Intensive Care, IRCCS Policlinico San Donato, Milan, Italy., de Somer F; Heart Centre, University Hospital Ghent, Gent, Belgium., Ravn HB; Department of Anaesthesiology and Intensive Care, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Jazyk:	angličtina
Zdroj:	Perfusion [Perfusion] 2024 Nov; Vol. 39 (8), pp. 1516-1530. Date of Electronic Publication: 2023 Oct 31.
DOI:	10.1177/02676591231211503
Abstrakt:	Cardiac Surgery-Associated Acute Kidney Injury (CSA-AKI) is a serious complication seen in approximately 20-30% of cardiac surgery patients. The underlying pathophysiology is complex, often involving both patient- and procedure related risk factors. In contrast to AKI occurring after other types of major surgery, the use of cardiopulmonary bypass comprises both additional advantages and challenges, including non-pulsatile flow, targeted blood flow and pressure as well as the ability to manipulate central venous pressure (congestion). With an increasing focus on the impact of CSA-AKI on both short and long-term mortality, early identification and management of high-risk patients for CSA-AKI has evolved. The present narrative review gives an up-to-date summary on definition, diagnosis, underlying pathophysiology, monitoring and implications of CSA-AKI, including potential preventive interventions. The review will provide the reader with an in-depth understanding of how to identify, support and provide a more personalized and tailored perioperative management to avoid development of CSA-AKI. Competing Interests: Declaration of conflicting interestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: MR is a consultant for Livanova and Medtronic. MR is the inventor of an algorithm based on CPB data and aimed to predict postoperative AKI. The remaining authors have no competing interest to declare.
Databáze:	MEDLINE
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