Ceftriaxone-Induced Encephalopathy in a Patient With End-Stage Renal Disease on Hemodialysis.
| Autor: | Nanjundappa A; Department of Internal Medicine, MedStar Franklin Square Medical Center, Baltimore, USA., Munankami S; Department of General Medicine, Kathmandu Medical College, Kathmandu, NPL., Al Talib K; Department of Nephrology, MedStar Franklin Square Medical Center, Baltimore, USA., Gummadi J; Department of Internal Medicine, MedStar Franklin Square Medical Center, Baltimore, USA., Bandaru SK; Department of Internal Medicine, MedStar Harbor Hospital, Baltimore, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Sep 29; Vol. 15 (9), pp. e46226. Date of Electronic Publication: 2023 Sep 29 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.46226 |
| Abstrakt: | Ceftriaxone-induced encephalopathy is a rare but known adverse effect secondary to neurotoxicity, especially in patients with end-stage renal disease (ESRD) on hemodialysis. The common presenting symptoms include myoclonus, psychosis, and seizures. We are presenting a case of a 77-year-old female patient who presented with confusion and jerky movements of her lips and extremities. Her initial workup was negative for stroke and seizure disorder. A probable diagnosis of ceftriaxone-induced encephalopathy was made using an Adverse Drug Reaction (ADR) probability scale (Naranjo scale) with a Naranjo score of 5. The patient's symptoms resolved after discontinuation of ceftriaxone. Ceftriaxone is a commonly used intravenous antibiotic in the inpatient setting, and thus clinicians should be aware of this rare adverse reaction in patients with ESRD. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Nanjundappa et al.) |
| Databáze: | MEDLINE |
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