Factors Influencing Individuals' Decision-Making Regarding Hematopoietic Stem Cell Donation: A Cross-Sectional Study in Saudi Arabia.

Autor:	AlSubaie RS; Family and Community Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., Alhamaid YA; Family and Community Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., Alali RS; Family and Community Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., Altaha MA; Family and Community Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., Aldalbahi AA; Family and Community Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU., Ibrahim Ali S; Family and Community Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Sep 26; Vol. 15 (9), pp. e46015. Date of Electronic Publication: 2023 Sep 26 (Print Publication: 2023).
DOI:	10.7759/cureus.46015
Abstrakt:	Introduction: Hematopoietic stem cell transplantation (HSCT) is a vital medical intervention for treating various conditions. The preferred methods, i.e., bone marrow transplantation and peripheral blood stem cell transplantation, have saved lives and attracted attention. Saudi Arabia, with a high sickle cell disease and leukemia incidence, faces the challenge of matching donors for HSCT. Factors like knowledge, attitudes, cultural beliefs, and access to information impact donation decisions. Methods: In May 2023, a cross-sectional online survey was conducted in Saudi Arabia, targeting the general population. Data were collected through an online questionnaire, analyzing demographics, knowledge, attitudes, and factors influencing donation intention. Results: Demographic analysis showed that females, younger individuals (18-25 years), those with higher education, and healthcare workers had better knowledge. Attitudes toward donation varied: 42.4% were willing to donate, while 57.6% were not. Psychological barriers, health concerns, pain, and inadequate knowledge influenced donation reluctance. Of the participants, 3.5% were registered stem cell donors, with 58.8% expressing willingness but not registered. Donors' intent was influenced by family members' need for transplants and knowledge. A majority (56.6%) supported employer support for health programs, while 65.7% believed government funding should assist donors. Conclusion: HSCT is vital in treating diseases like sickle cell and leukemia in Saudi Arabia. While many recognize its importance, knowledge gaps about its specifics and donation deter potential donors. Enhanced awareness campaigns and support from employers and the government could increase donor registrations. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, AlSubaie et al.)
Databáze:	MEDLINE
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