Vaccination Recommendations in Solid Organ Transplant Adult Candidates and Recipients.

Autor: Viganò M; Gastroenterology Hepatology and Transplantation Unit, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Beretta M; Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Lepore M; Unit of Nephrology and Dialysis, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Abete R; Cardiology Division, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Benatti SV; Infectious Diseases Unit, ASST Papa Giovanni XXII, 24127 Bergamo, Italy., Grassini MV; Gastroenterology Hepatology and Transplantation Unit, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy.; Section of Gastroenterology & Hepatology, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties, PROMISE, University of Palermo, 90128 Palermo, Italy., Camagni S; Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Chiodini G; Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Vargiu S; Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Vittori C; Cardiology Division, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Iachini M; Unit of Nephrology and Dialysis, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Terzi A; Cardiothoracic Department, ASST Papa Giovanni XXII, 24127 Bergamo, Italy., Neri F; Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Pinelli D; Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Casotti V; Pediatric Hepatology, Gastroenterology and Transplantation Unit, ASST Papa Giovanni XXII, 24127 Bergamo, Italy., Di Marco F; Pulmonary Medicine Unit, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy.; Department of Health Sciences, University of Milan, 20158 Milan, Italy., Ruggenenti P; Unit of Nephrology and Dialysis, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy.; Department of Renal Medicine, Clinical Research Centre for Rare Diseases 'Aldo e Cele Daccò', Institute of Pharmacologic Research 'Mario Negri IRCCS', Ranica, 24020 Bergamo, Italy., Rizzi M; Infectious Diseases Unit, ASST Papa Giovanni XXII, 24127 Bergamo, Italy., Colledan M; Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy., Fagiuoli S; Gastroenterology Hepatology and Transplantation Unit, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy.; Department of Medicine, University of Milan Bicocca, 20126 Milan, Italy.
Jazyk: angličtina
Zdroj: Vaccines [Vaccines (Basel)] 2023 Oct 18; Vol. 11 (10). Date of Electronic Publication: 2023 Oct 18.
DOI: 10.3390/vaccines11101611
Abstrakt: Prevention of infections is crucial in solid organ transplant (SOT) candidates and recipients. These patients are exposed to an increased infectious risk due to previous organ insufficiency and to pharmacologic immunosuppression. Besides infectious-related morbidity and mortality, this vulnerable group of patients is also exposed to the risk of acute decompensation and organ rejection or failure in the pre- and post-transplant period, respectively, since antimicrobial treatments are less effective than in the immunocompetent patients. Vaccination represents a major preventive measure against specific infectious risks in this population but as responses to vaccines are reduced, especially in the early post-transplant period or after treatment for rejection, an optimal vaccination status should be obtained prior to transplantation whenever possible. This review reports the currently available data on the indications and protocols of vaccination in SOT adult candidates and recipients.
Databáze: MEDLINE
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