Autor: |
Lorenzo-Villegas DL; Faculty of Health Sciences, University Fernando Pessoa-Canarias, 35450 Santa Maria de Guia, Spain., Gohil NV; Department of Internal Medicne, Medical College Baroda, Vadodara 390001, India.; Department of Internal Medicne, SSG Hospital Vadodara, Gotri, Vadodara 390021, India., Lamo P; Escuela Superior de Ingeniería y Tecnología, Universidad Internacional de La Rioja, 26006 Logroño, Spain., Gurajala S; College of Applied Medical Sciences in Jubail, Imam Abdulrahman bin Faisal University, Dammam 31441, Saudi Arabia., Bagiu IC; Department of Microbiology, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.; Multidisciplinary Research Center on Antimicrobial Resistance (MULTI-REZ), Microbiology Department, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania., Vulcanescu DD; Department of Microbiology, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.; Multidisciplinary Research Center on Antimicrobial Resistance (MULTI-REZ), Microbiology Department, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania., Horhat FG; Department of Microbiology, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania.; Multidisciplinary Research Center on Antimicrobial Resistance (MULTI-REZ), Microbiology Department, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania., Sorop VB; Department of Obstetrics and Gynecology, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania., Diaconu M; Department of Obstetrics and Gynecology, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania., Sorop MI; Doctoral School, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania., Oprisoni A; Department of Pediatrics, Discipline of Pediatric Oncology and Hematology, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania., Horhat RM; Department of Conservative Dentistry and Endodontics, Faculty of Dental Medicine, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, Romania., Susan M; Centre for Preventive Medicine, Department of Internal Medicine, 'Victor Babes' University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, Romania., MohanaSundaram A; School of Pharmacy, Sathyabama Institute of Science and Technology, Jeppiaar Nagar, Rajiv Gandhi Salai, Chennai 600119, India. |
Abstrakt: |
Candida is the largest genus of medically significant fungi. Although most of its members are commensals, residing harmlessly in human bodies, some are opportunistic and dangerously invasive. These have the ability to cause severe nosocomial candidiasis and candidemia that affect the viscera and bloodstream. A prompt diagnosis will lead to a successful treatment modality. The smart solution of biosensing technologies for rapid and precise detection of Candida species has made remarkable progress. The development of point-of-care (POC) biosensor devices involves sensor precision down to pico-/femtogram level, cost-effectiveness, portability, rapidity, and user-friendliness. However, futuristic diagnostics will depend on exploiting technologies such as multiplexing for high-throughput screening, CRISPR, artificial intelligence (AI), neural networks, the Internet of Things (IoT), and cloud computing of medical databases. This review gives an insight into different biosensor technologies designed for the detection of medically significant Candida species, especially Candida albicans and C. auris , and their applications in the medical setting. |