| Autor: |
Taddei P; Biochemistry Unit, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy., Di Foggia M; Biochemistry Unit, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy., Zamparini F; Endodontic Clinical Section, Unit of Odontostomatological Sciences, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via San Vitale 59, 40136 Bologna, Italy., Prati C; Endodontic Clinical Section, Unit of Odontostomatological Sciences, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via San Vitale 59, 40136 Bologna, Italy., Gandolfi MG; Laboratory of Biomaterials and Oral Pathology, Unit of Odontostomatological Sciences, Department of Biomedical and Neuromotor Sciences, University of Bologna, Via San Vitale 59, 40136 Bologna, Italy. |
| Abstrakt: |
Guttapercha (GP, trans-1,4-polyisoprene) is the most used tooth root filling material, and it must be used with an appropriate cement (typically a polydimethylsiloxane (PDMS)-based sealer) to ensure an adequate canal obturation. This study aimed to assess the bioactivity and dentin remineralization ability of a bioglass containing PDMS commercial endodontic sealer, BG-PDMS (GuttaFlow Bioseal), and to evaluate the possible influence of a GP cone (Roeko GP point) on the mineralization process. To this end, BG-PDMS disks were aged alone or in the presence of a GP cone in Hank's Balanced Salt Solution (28 d, 37 °C). Dentin remineralization experiments were carried out under the same conditions. Micro-Raman and IR analyses demonstrated that BG-PDMS is bioactive, thanks to the formation of a silica-rich layer with nucleation sites for B-type carbonated apatite deposition. This phase was thicker when BG-PDMS was aged in the presence of GP. The two materials influenced each other because GP, which alone did not show any bioactivity, nucleated a calcium phosphate phase under these conditions. Analogously, dentin remineralization experiments showed that BG-PDMS is able to remineralize dentin, especially in the presence of GP. Under the experimental conditions, GP acted as a templating agent for calcium phosphate deposition. |
