Iturin: A Promising Cyclic Lipopeptide with Diverse Applications.

Autor: Yaraguppi DA; Department of Biotechnology, KLE Technological University, Hubballi 580031, Karnataka, India., Bagewadi ZK; Department of Biotechnology, KLE Technological University, Hubballi 580031, Karnataka, India., Patil NR; Department of Physics, B. V Bhoomaraddi College of Engineering and Technology, Hubballi 580031, Karnataka, India., Mantri N; The Pangenomics Lab, School of Science, RMIT University, Bundoora, VIC 3083, Australia.; The UWA Institute of Agriculture, The University of Western Australia, Perth, WA 6009, Australia.
Jazyk: angličtina
Zdroj: Biomolecules [Biomolecules] 2023 Oct 12; Vol. 13 (10). Date of Electronic Publication: 2023 Oct 12.
DOI: 10.3390/biom13101515
Abstrakt: This comprehensive review examines iturin, a cyclic lipopeptide originating from Bacillus subtilis and related bacteria. These compounds are structurally diverse and possess potent inhibitory effects against plant disease-causing bacteria and fungi. Notably, Iturin A exhibits strong antifungal properties and low toxicity, making it valuable for bio-pesticides and mycosis treatment. Emerging research reveals additional capabilities, including anticancer and hemolytic features. Iturin finds applications across industries. In food, iturin as a biosurfactant serves beyond surface tension reduction, enhancing emulsions and texture. Biosurfactants are significant in soil remediation, agriculture, wound healing, and sustainability. They also show promise in Microbial Enhanced Oil Recovery (MEOR) in the petroleum industry. The pharmaceutical and cosmetic industries recognize iturin's diverse properties, such as antibacterial, antifungal, antiviral, anticancer, and anti-obesity effects. Cosmetic applications span emulsification, anti-wrinkle, and antibacterial use. Understanding iturin's structure, synthesis, and applications gains importance as biosurfactant and lipopeptide research advances. This review focuses on emphasizing iturin's structural characteristics, production methods, biological effects, and applications across industries. It probes iturin's antibacterial, antifungal potential, antiviral efficacy, and cancer treatment capabilities. It explores diverse applications in food, petroleum, pharmaceuticals, and cosmetics, considering recent developments, challenges, and prospects.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje