Clinical and Radiological Parameters to Discriminate Tuberculous Peritonitis and Peritoneal Carcinomatosis.

Autor: Jha DK; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India., Gupta P; Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India., Neelam PB; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India., Kumar R; Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India., Krishnaraju VS; Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India., Rohilla M; Department of Cytopathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India., Prasad AS; Department of Gastroenterology, Army Hospital Research and Referral, New Delhi 110010, India., Dutta U; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India., Sharma V; Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Jazyk: angličtina
Zdroj: Diagnostics (Basel, Switzerland) [Diagnostics (Basel)] 2023 Oct 13; Vol. 13 (20). Date of Electronic Publication: 2023 Oct 13.
DOI: 10.3390/diagnostics13203206
Abstrakt: It is challenging to differentiate between tuberculous peritonitis and peritoneal carcinomatosis due to their insidious nature and intersecting symptoms. Computed tomography (CT) is the modality of choice in evaluating diffuse peritoneal disease. We conducted an ambispective analysis of patients suspected as having tuberculous peritonitis or peritoneal tuberculosis between Jan 2020 to Dec 2021. The study aimed to identify the clinical and radiological features differentiating the two entities. We included 44 cases of tuberculous peritonitis and 45 cases of peritoneal carcinomatosis, with a median age of 31.5 (23.5-40) and 52 (46-61) years, respectively ( p ≤ 0.001). Fever, past history of tuberculosis, and loss of weight were significantly associated with tuberculous peritonitis ( p ≤ 0.001, p = 0.038 and p = 0.001). Pain in the abdomen and history of malignancy were significantly associated with peritoneal carcinomatosis ( p = 0.038 and p ≤ 0.001). Ascites was the most common radiological finding. Loculated ascites, splenomegaly and conglomeration of lymph nodes predicted tuberculous peritonitis significantly ( p ≤ 0.001, p = 0.010, p = 0.038). Focal liver lesion(s) and nodular omental involvement were significantly associated with peritoneal carcinomatosis ( p = 0.011, p = 0.029). The use of clinical features in conjunction with radiological findings provide better diagnostic yields because of overlapping imaging findings.
Databáze: MEDLINE
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