Live birth rates after resolution of endometrial cavity fluid in frozen embryo transfer cycles.

Autor: Nguyen V; Dept of Obstetrics and Gynecology, University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8M5, Canada. vincnguyen@toh.ca., Jackson A; Dept of Obstetrics and Gynecology, University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8M5, Canada.; Ottawa Fertility Centre, Green Valley Crescent, Ottawa, ON, 100-955, K2C 3V4, Canada., Gale J; Dept of Obstetrics and Gynecology, University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8M5, Canada.; Ottawa Fertility Centre, Green Valley Crescent, Ottawa, ON, 100-955, K2C 3V4, Canada.
Jazyk: angličtina
Zdroj: Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2023 Oct 27; Vol. 21 (1), pp. 100. Date of Electronic Publication: 2023 Oct 27.
DOI: 10.1186/s12958-023-01149-8
Abstrakt: Research Question: Are live birth rates affected in frozen embryo transfer cycles that develop transient endometrial cavity fluid that resolves by day of embryo transfer?
Design: The first frozen blastocyst transfer cycle between January 1st, 2016 and December 31st, 2019 were included in this retrospective cohort study at an academic fertility center. The presence or absence of endometrial cavity fluid (ECF) detected on initial ultrasound and at time of transfer was recorded. Patients who had persistent ECF at time of transfer were excluded from the study. The primary outcome was live birth rate in the group with resolved ECF relative to the group without ECF.
Results: A total of 1034 frozen blastocyst transfer cycles were included, 54 with resolved ECF and 980 without ECF. Adjusted analyses were performed using a log-binomial regression model. Live birth rates were 35.2% and 34.2%, adjusted risk ratio 1.00 [95% CI 0.70-1.50] in the two groups, respectively.
Conclusion: Live birth rates in frozen embryo transfer cycles are equivalent between patients with resolved endometrial cavity fluid compared to those who never had endometrial cavity fluid. Our findings suggest that the presence of endometrial cavity fluid is likely not detrimental to live birth rates if the fluid spontaneously resolves by the time of embryo transfer.
(© 2023. The Author(s).)
Databáze: MEDLINE
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