Repeated Low-level Red-light Therapy: The Next Wave in Myopia Management?

Autor:	Salzano AD, Khanal S; Department of Optometry and Vision Science, University of Alabama at Birmingham, Birmingham, Alabama., Cheung NL; Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina., Weise KK; Department of Optometry and Vision Science, University of Alabama at Birmingham, Birmingham, Alabama., Jenewein EC; Pennsylvania College of Optometry, Salus University, Elkins Park, Pennsylvania., Horn DM; Pennsylvania College of Optometry, Salus University, Elkins Park, Pennsylvania., Mutti DO; The Ohio State University College of Optometry, Columbus, Ohio., Gawne TJ; Department of Optometry and Vision Science, University of Alabama at Birmingham, Birmingham, Alabama.
Jazyk:	angličtina
Zdroj:	Optometry and vision science : official publication of the American Academy of Optometry [Optom Vis Sci] 2023 Dec 01; Vol. 100 (12), pp. 812-822. Date of Electronic Publication: 2023 Oct 25.
DOI:	10.1097/OPX.0000000000002083
Abstrakt:	Significance: Exposure to long-wavelength light has been proposed as a potential intervention to slow myopia progression in children. This article provides an evidence-based review of the safety and myopia control efficacy of red light and discusses the potential mechanisms by which red light may work to slow childhood myopia progression.The spectral composition of the ambient light in the visual environment has powerful effects on eye growth and refractive development. Studies in mammalian and primate animal models (macaque monkeys and tree shrews) have shown that daily exposure to long-wavelength (red or amber) light promotes slower eye growth and hyperopia development and inhibits myopia induced by form deprivation or minus lens wear. Consistent with these results, several recent randomized controlled clinical trials in Chinese children have demonstrated that exposure to red light for 3 minutes twice a day significantly reduces myopia progression and axial elongation. These findings have collectively provided strong evidence for the potential of using red light as a myopia control intervention in clinical practice. However, several questions remain unanswered. In this article, we review the current evidence on the safety and efficacy of red light as a myopia control intervention, describe potential mechanisms, and discuss some key unresolved issues that require consideration before red light can be broadly translated into myopia control in children. Competing Interests: Conflict of Interest Disclosure: None of the authors have reported a financial conflict of interest. There was no sponsorship for the submitted review. (Copyright © 2023 American Academy of Optometry.)
Databáze:	MEDLINE
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