Reduced TiO 2 Nanotubes/Silk Fibroin/ZnO as a Promising Hybrid Antibacterial Coating.

Autor: Păun AG; Department of General Chemistry, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, Gheorghe Polizu 1-7 street, Bucharest, 011061, Romania., Popescu S; Department of General Chemistry, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, Gheorghe Polizu 1-7 street, Bucharest, 011061, Romania., Ungureanu C; Department of General Chemistry, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, Gheorghe Polizu 1-7 street, Bucharest, 011061, Romania., Trusca R; National Center for Micro and Nanomaterials, National University of Science and Technology Politehnica Bucharest, Splaiul Independentei 313, 060042, Bucharest, Romania., Pirvu C; Department of General Chemistry, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, Gheorghe Polizu 1-7 street, Bucharest, 011061, Romania.
Jazyk: angličtina
Zdroj: ChemPlusChem [Chempluschem] 2024 Mar; Vol. 89 (3), pp. e202300450. Date of Electronic Publication: 2023 Nov 20.
DOI: 10.1002/cplu.202300450
Abstrakt: The current research aims to elucidate the influence of reduction process of TiO 2 nanostructures on the surface properties of a bioinspired Ti modified implant, considering that the interface between a biomaterial surface and the living tissue plays an important role for this interaction. The production of reduced TiO 2 nanotubes (RNT) with lower band gap is optimized and their performance is compared with those of simple TiO 2 nanotubes (NT). The more conductive surfaces provided by the presence of RNT on Ti, allow a facile deposition of silk fibroin (SF) film using the electrochemical deposition method. This hybrid film is then functionalized with ZnO nanoparticles, to improve the antibacterial effect of the coating. The modified Ti surface is evaluated in terms of surface chemistry, morphology and roughness, wettability, surface energy, surface charge and antibacterial properties. Surface analysis such as SEM, AFM, FTIR and contact angle measurements were performed to obtain topographical features and wettability. FT-IR analysis confirms that SF was effectively attached to TiO 2 nanotubes surfaces. The electrochemical deposition of SF and SF-ZnO reduced the interior diameter of nanotubes from ~85 nm to approx. 50-60 nm. All modified surfaces have a hydrophilic character.
(© 2023 Wiley-VCH GmbH.)
Databáze: MEDLINE
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