| Autor: |
Gatto ML; Department of Industrial Engineering and Mathematical Sciences (DIISM), Marche Polytechnic University, Via Brecce Bianche 12, 60131 Ancona, Italy., Cerqueni G; Department DISCLIMO & UdR INSTM, Marche Polytechnic University, Via Tronto 10/a, 60126 Ancona, Italy., Groppo R; 3D4MEC S.r.l., Via Porrettana 48, 40037 Sasso Marconi, Italy., Tognoli E; Department of Engineering 'Enzo Ferrari', University of Modena and Reggio Emilia, Via Vivarelli 10, 41125 Modena, Italy., Santoni A; Department of Industrial Engineering and Mathematical Sciences (DIISM), Marche Polytechnic University, Via Brecce Bianche 12, 60131 Ancona, Italy., Cabibbo M; Department of Industrial Engineering and Mathematical Sciences (DIISM), Marche Polytechnic University, Via Brecce Bianche 12, 60131 Ancona, Italy., Mattioli-Belmonte M; Department DISCLIMO & UdR INSTM, Marche Polytechnic University, Via Tronto 10/a, 60126 Ancona, Italy., Mengucci P; Department SIMAU & UdR INSTM, Università Politecnica delle Marche, Via Brecce Bianche 12, 60131 Ancona, Italy. |
| Abstrakt: |
This experimental study aims to extend the know-how on biomechanical performances of duplex stainless steel (DSS) for tissue engineering applications to a graded lattice geometry scaffold based on the F53 DSS (UNS S32750 according to ASTM A182) produced by laser powder bed fusion (LPBF). The same dense-out graded geometry based on rhombic dodecahedral elementary unit cells investigated in previous work on 316L stainless steel (SS) was adopted here for the manufacturing of the F53 DSS scaffold (SF53). Microstructural characterization and mechanical and biological tests were carried out on the SF53 scaffold, using the in vitro behavior of the 316L stainless steel scaffold (S316L) as a control. Results show that microstructure developed as a consequence of different volume energy density (VED) values is mainly responsible for the different mechanical behaviors of SF53 and S316L, both fabricated using the same LPBF manufacturing system. Specifically, the ultimate compressive strength (σUC) and elastic moduli (E) of SF53 are three times and seven times higher than S316L, respectively. Moreover, preliminary biological tests evidenced better cell viability in SF53 than in S316L already after seven days of culture, suggesting SF53 with dense-out graded geometry as a viable alternative to 316L SS for bone tissue engineering applications. |
