Basal Cell Carcinoma in the Periungual Region: A Rare Case and Pathogenesis Insights.
| Autor: | Martinez-Ortega JI; Dermatology, Dermatological Institute of Jalisco 'Dr. Jose Barba Rubio', Zapopan, MEX., Perez Hernandez FJ; Department of Internal Medicine, High Specialty Regional Hospital of the Yucatan Peninsula, Merida, MEX., Reyes Garcia LN; Dermatology, Hospital Universitario Clinico Quirurgico Comandante 'Manuel Fajardo', La Habana, CUB. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Sep 25; Vol. 15 (9), pp. e45934. Date of Electronic Publication: 2023 Sep 25 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.45934 |
| Abstrakt: | This case report presents a rare occurrence of basal cell carcinoma (BCC) in the periungual region of the thumb. BCC is the most common type of skin cancer, typically found in sun-exposed areas. The discussion explores the underlying pathogenesis mechanisms, including the role of ultraviolet exposure, the absence of pilosebaceous units, and the involvement of the sonic hedgehog (SHH) pathway. Understanding the complexities of BCC in atypical locations is essential for effective prevention and treatment strategies. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Martinez-Ortega et al.) |
| Databáze: | MEDLINE |
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