Metallic Materials for Bone Repair.

Autor: Fan L; Beijing Research Institute of Traumatology and Orthopaedics, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, China., Chen S; Institute for Frontier Science, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, China., Yang M; Department of Orthopaedics and Traumatology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, China., Liu Y; Beijing Research Institute of Traumatology and Orthopaedics, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, China.; Department of Spine Surgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, China., Liu J; Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China.
Jazyk: angličtina
Zdroj: Advanced healthcare materials [Adv Healthc Mater] 2024 Jan; Vol. 13 (3), pp. e2302132. Date of Electronic Publication: 2023 Nov 12.
DOI: 10.1002/adhm.202302132
Abstrakt: Repair of large bone defects caused by trauma or disease poses significant clinical challenges. Extensive research has focused on metallic materials for bone repair because of their favorable mechanical properties, biocompatibility, and manufacturing processes. Traditional metallic materials, such as stainless steel and titanium alloys, are widely used in clinics. Biodegradable metallic materials, such as iron, magnesium, and zinc alloys, are promising candidates for bone repair because of their ability to degrade over time. Emerging metallic materials, such as porous tantalum and bismuth alloys, have gained attention as bone implants owing to their bone affinity and multifunctionality. However, these metallic materials encounter many practical difficulties that require urgent improvement. This article systematically reviews and analyzes the metallic materials used for bone repair, providing a comprehensive overview of their morphology, mechanical properties, biocompatibility, and in vivo implantation. Furthermore, the strategies and efforts made to address the short-comings of metallic materials are summarized. Finally, the perspectives for the development of metallic materials to guide future research and advancements in clinical practice are identified.
(© 2023 Wiley-VCH GmbH.)
Databáze: MEDLINE
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