Web-Based Cognitive Bias Modification Program for Young People With Social Anxiety and Hazardous Alcohol Use: Feasibility, Acceptability, and Preliminary Efficacy Study.

Autor:	Prior K; Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, Australia., Salemink E; Experimental Psychopathology Lab, Department of Clinical Psychology, Utrecht University, Utrecht, Netherlands., Piggott M; Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, Australia., Manning V; Eastern Health Clinical School, Faculty of Medicine, Nursing & Health Sciences, Monash University, Melbourne, Australia., Wiers RW; Addiction Development and Psychopathology (ADAPT)-lab, Department of Psychology, University of Amsterdam, Amsterdam, Netherlands., Teachman BA; Department of Psychology, School of Arts and Sciences, University of Virginia, Charlottesville, VA, United States., Teesson M; Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, Australia., Baillie AJ; Sydney School of Health Sciences, Faculty of Medicine & Health, The University of Sydney, Sydney, Australia., Mahoney A; Clinical Research Unit for Anxiety and Depression, St Vincent's Public Hospital, Sydney, Australia.; School of Psychiatry, University of New South Wales, Sydney, Australia., McLellan L; Centre for Emotional Health, Department of Psychology, Macquarie University, Sydney, Australia., Newton NC; Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, Australia., Stapinski LA; Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, Australia.
Jazyk:	angličtina
Zdroj:	JMIR formative research [JMIR Form Res] 2023 Oct 25; Vol. 7, pp. e46008. Date of Electronic Publication: 2023 Oct 25.
DOI:	10.2196/46008
Abstrakt:	Background: Interpretation bias modification (IBM) and approach bias modification (ApBM) cognitive retraining interventions can be efficacious adjunctive treatments for improving social anxiety and alcohol use problems. However, previous trials have not examined the combination of these interventions in a young, comorbid sample. Objective: This study aims to describe the feasibility, acceptability, and preliminary efficacy of a web-based IBM+ApBM program for young adults with social anxiety and hazardous alcohol use ("Re-Train Your Brain") when delivered in conjunction with treatment as usual (TAU). Methods: The study involved a 3-arm randomized controlled pilot trial in which treatment-seeking young adults (aged 18-30 y) with co-occurring social anxiety and hazardous alcohol use were randomized to receive (1) the "integrated" Re-Train Your Brain program, where each session included both IBM and ApBM (50:50 ratio), plus TAU (35/100, 35%); (2) the "alternating" Re-Train Your Brain program, where each session focused on IBM or ApBM in an alternating pattern, plus TAU (32/100, 32%); or (3) TAU only (33/100, 33%). Primary outcomes included feasibility and acceptability, and secondary efficacy outcomes included changes in cognitive biases, social anxiety symptoms, and alcohol use. Assessments were conducted at baseline, after the intervention period (6 weeks after baseline), and 12 weeks after baseline. Results: Both Re-Train Your Brain program formats were feasible and acceptable for young adults. When coupled with TAU, both integrated and alternating programs resulted in greater self-reported improvements than TAU only in anxiety interpretation biases (at the 6-week follow-up; Cohen d=0.80 and Cohen d=0.89) and comorbid interpretation biases (at the 12-week follow-up; Cohen d=1.53 and Cohen d=1.67). In addition, the alternating group reported larger improvements over the control group in generalized social anxiety symptoms (at the 12-week follow-up; Cohen d=0.83) and alcohol cravings (at the 6-week follow-up; Cohen d=0.81). There were null effects on all other variables and no differences between the intervention groups in efficacy outcomes. Conclusions: Should these findings be replicated in a larger randomized controlled trial, Re-Train Your Brain has the potential to be a scalable, low-cost, and non-labor-intensive adjunct intervention for targeting interpretation and comorbidity biases as well as generalized anxiety and alcohol-related outcomes in the real world. Trial Registration: Australian New Zealand Clinical Trials Registry ACTRN12620001273976; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=364131. International Registered Report Identifier (irrid): RR2-10.2196/28667. (©Katrina Prior, Elske Salemink, Monique Piggott, Victoria Manning, Reinout W Wiers, Bethany A Teachman, Maree Teesson, Andrew J Baillie, Alison Mahoney, Lauren McLellan, Nicola C Newton, Lexine A Stapinski. Originally published in JMIR Formative Research (https://formative.jmir.org), 25.10.2023.)
Databáze:	MEDLINE
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