A Strategy for Rescuing a Child From Clonazepam Poisoning: A Case Study.
| Autor: | Zhao X; Department of Pharmacy, Qingdao West Coast New Area People's Hospital, Qingdao, China., Zhang R; Department of Pharmacy, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China; and., Li W; Department of Pharmacy, Children's Hospital of Nanjing Medical University, Nanjing, China. |
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| Jazyk: | angličtina |
| Zdroj: | Therapeutic drug monitoring [Ther Drug Monit] 2024 Apr 01; Vol. 46 (2), pp. 138-140. Date of Electronic Publication: 2023 Oct 23. |
| DOI: | 10.1097/FTD.0000000000001148 |
| Abstrakt: | Background: This report describes the successful rescue of a 12-year-old girl who ingested large quantities of clonazepam tablets. Methods: The patient was promptly treated with flumazenil and hemoperfusion to alleviate the symptoms of central depression. Therapeutic drug monitoring was used to evaluate detoxification efficacy. The authors analyzed the rescue protocol for clonazepam poisoning based on the pathophysiology, clinical manifestations, and pharmacokinetics of clonazepam overdose. Results: The patient responded well to the treatment and was discharged from the hospital without adverse events. Conclusions: This case study demonstrated the effectiveness and safety of combining flumazenil with hemoperfusion as a treatment for clonazepam poisoning. This study aimed to provide insights into more effective methods for treating clonazepam overdose and contribute to the ongoing issue of managing this condition. Competing Interests: The authors declare no conflict of interest. (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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