| Autor: |
Moirano G; Department of Medical Sciences, University of Turin, Turin, Italy.; Postgraduate School of Biostatistics, Department of Public Health and Paediatrics, University of Turin, Turin, Italy., Botta A; Department of Infectious Disease and Infectious Emergencies, AORN Monaldi-Cotugno-CTO, Naples, Italy., Yang M; Hypertension Unit, Division of Internal Medicine, Department of Medical Sciences, University of Turin, Turin, Italy., Mangeruga M; Environmental Technology, Centre for Environmental Policy, Imperial College, London, UK., Murray K; Medical Research Council Unit The Gambia at the London School of Hygiene & Tropical Medicine, Banjul, The Gambia.; Centre on Climate Change and Planetary Health, London School of Hygiene & Tropical Medicine, London, UK., Vineis P; School of Public Health, Imperial College, Medical Research Council (MRC) Centre for Environment and Health, London, UK. |
| Abstrakt: |
Previous studies suggest that the risk of human infection by hantavirus, a family of rodent-borne viruses, might be affected by different environmental determinants such as land cover, land use and land use change. This study examined the association between land-cover, land-use, land use change, and human hantavirus infection risk. PubMed and Scopus databases were interrogated using terms relative to land use (change) and human hantavirus disease. Screening and selection of the articles were completed by three independent reviewers. Classes of land use assessed by the different studies were categorized into three macro-categories of exposure ('Agriculture', 'Forest Cover', 'Urban Areas') to qualitatively synthesize the direction of the association between exposure variables and hantavirus infection risk in humans. A total of 25 articles were included, with 14 studies (56%) conducted in China, 4 studies (16%) conducted in South America and 7 studies (28%) conducted in Europe. Most of the studies (88%) evaluated land cover or land use, while 3 studies (12%) evaluated land use change, all in relation to hantavirus infection risk. We observed that land cover and land-use categories could affect hantavirus infection incidence. Overall, agricultural land use was positively associated with increased human hantavirus infection risk, particularly in China and Brazil. In Europe, a positive association between forest cover and hantavirus infection incidence was observed. Studies that assessed the relationship between built-up areas and hantavirus infection risk were more variable, with studies reporting positive, negative or no associations. |
