Ciliary dyskinesia in severe asthma is not affected by chronic mucus hypersecretion.

Autor:	Kempeneers C; Division of Respirology, Department of Pediatrics, University Hospital Liège, Liège, Belgium.; Pneumology laboratory, I3 Group, GIGA Research Center, University of Liège, Liège, Belgium., Bonhiver R; Division of Respirology, Department of Pediatrics, University Hospital Liège, Liège, Belgium.; Pneumology laboratory, I3 Group, GIGA Research Center, University of Liège, Liège, Belgium., Bricmont N; Division of Respirology, Department of Pediatrics, University Hospital Liège, Liège, Belgium.; Pneumology laboratory, I3 Group, GIGA Research Center, University of Liège, Liège, Belgium., Pirotte M; Division of Respirology, Department of Pediatrics, University Hospital Liège, Liège, Belgium., Engelskirchen S; Division of Respirology, Department of Pediatrics, University Hospital Liège, Liège, Belgium.; Pneumology laboratory, I3 Group, GIGA Research Center, University of Liège, Liège, Belgium., Benchimol L; Department of ENT, University Hospital Liège, Liège, Belgium., Calmes D; Department of Pneumology, University Hospital Liège, Liège, Belgium., Guissard F; Department of Pneumology, University Hospital Liège, Liège, Belgium., Moermans C; Pneumology laboratory, I3 Group, GIGA Research Center, University of Liège, Liège, Belgium.; Department of Pneumology, University Hospital Liège, Liège, Belgium., Seghaye MC; Pneumology laboratory, I3 Group, GIGA Research Center, University of Liège, Liège, Belgium.; Division of Cardiology, Department of Pediatrics, University Hospital Liège and University of Liège, Liège, Belgium., Louis R; Pneumology laboratory, I3 Group, GIGA Research Center, University of Liège, Liège, Belgium.; Department of Pneumology, University Hospital Liège, Liège, Belgium., Schleich F; Pneumology laboratory, I3 Group, GIGA Research Center, University of Liège, Liège, Belgium.; Department of Pneumology, University Hospital Liège, Liège, Belgium.
Jazyk:	angličtina
Zdroj:	ERJ open research [ERJ Open Res] 2023 Oct 02; Vol. 9 (5). Date of Electronic Publication: 2023 Oct 02 (Print Publication: 2023).
DOI:	10.1183/23120541.00220-2023
Abstrakt:	Chronic mucus hypersecretion (CMH) is linked to increased asthma severity. Ciliary dyskinesia is present in severe asthma but CMH was not associated with a worse ciliary dysfunction, suggesting another mechanism to explain chronic cough and phlegm. https://bit.ly/3JNUgGr. Competing Interests: Conflict of interest: C. Kempeneers has received consulting fees from Sanofi (international advisory board). R. Louis and F. Schleich have received educational and research grants from GSK, AstraZeneca and Chiesi; consulting fees from GSK and AstraZeneca (national and international advisory boards); and lecture fees from GSK, AstraZeneca and Chiesi. F. Schleich has received lecture fees from TEVA. R. Bonhiver, N. Bricmont, M. Pirotte, S. Engelskirchen, L. Benchimol, D. Calmes, F. Guissard, C. Moermans and M-C. Seghaye have no conflicts to declare. (Copyright ©The authors 2023.)
Databáze:	MEDLINE
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