Flagellar polymorphism-dependent bacterial swimming motility in a structured environment.
| Autor: | Kinosita Y; CPR, RIKEN, Wako, Saitama 351-0198, Japan., Sowa Y; Department of Frontier Bioscience, Hosei University, Tokyo 184-8584, Japan.; Research Center for Micro-Nano Technology, Hosei University, Tokyo 184-8584, Japan. |
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| Jazyk: | angličtina |
| Zdroj: | Biophysics and physicobiology [Biophys Physicobiol] 2023 May 30; Vol. 20 (2), pp. e200024. Date of Electronic Publication: 2023 May 30 (Print Publication: 2023). |
| DOI: | 10.2142/biophysico.bppb-v20.0024 |
| Abstrakt: | Most motile bacteria use supramolecular motility machinery called bacterial flagellum, which converts the chemical energy gained from ion flux into mechanical rotation. Bacterial cells sense their external environment through a two-component regulatory system consisting of a histidine kinase and response regulator. Combining these systems allows the cells to move toward favorable environments and away from their repellents. A representative example of flagellar motility is run-and-tumble swimming in Escherichia coli , where the counter-clockwise (CCW) rotation of a flagellar bundle propels the cell forward, and the clockwise (CW) rotation undergoes cell re-orientation (tumbling) upon switching the direction of flagellar motor rotation from CCW to CW. In this mini review, we focus on several types of chemotactic behaviors that respond to changes in flagellar shape and direction of rotation. Moreover, our single-cell analysis demonstrated back-and-forth swimming motility of an original E. coli strain. We propose that polymorphic flagellar changes are required to enhance bacterial movement in a structured environment as a colony spread on an agar plate. Competing Interests: The authors declare there are no competing financial interests. (2023 THE BIOPHYSICAL SOCIETY OF JAPAN.) |
| Databáze: | MEDLINE |
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