A unique case of lymphoepithelioma-like HCC with osteoclast-like giant cells: CT imaging features with pathologic correlations.

Autor: Frittoli B; Department of Radiology, ASST Spedali Civili, Brescia, Italy., Castaldo A; Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy., Santarsiere M; Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy., Ascione R; Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy., Tanzi G; Department of Pathology, ASST Cremona, Cremona, Italy., Ponsiglione A; Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy. a.ponsiglionemd@gmail.com., Baiocchi GL; Department of Clinical and Experimental Sciences, Surgical Clinic, University of Brescia, Brescia, Italy.; Department of Surgery, ASST Cremona, Cremona, Italy., Grazioli L; Department of Radiology, ASST Spedali Civili, Brescia, Italy.
Jazyk: angličtina
Zdroj: Clinical journal of gastroenterology [Clin J Gastroenterol] 2024 Feb; Vol. 17 (1), pp. 112-117. Date of Electronic Publication: 2023 Oct 21.
DOI: 10.1007/s12328-023-01871-1
Abstrakt: Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver, with several histological variants being reported in literature. Hereby, we describe a case of a 77-year-old man with chronic liver disease referred to our department for performing a computed tomography (CT) due to a liver mass discovered at an abdominal ultrasound follow-up. At CT, a large, ill-defined lesion in the third hepatic segment was detected, characterized by progressive and delayed enhancement with minimal retraction of the hepatic capsule, associated with perihepatic adipose tissue inhomogeneity, mimicking a cholangiocarcinoma. At histopathological evaluation, the lesion turned out to be an HCC with lymphoepithelioma-like component and osteoclastic-like giant cells. This report focuses on the clinicopathological and radiological features of this unique case.
(© 2023. The Author(s).)
Databáze: MEDLINE
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