Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals.

Autor: Alshahrani SH; Medical Surgical Nursing Department, King Khalid University, Khamis Mushate, Saudi Arabia., Atia YA; Department of Medical Chemistry, Al-Kindy College of Medicine, University of Baghdad, University of Baghdad, Baghdad, Iraq. yasirabas@kmc.uobaghdad.edu.iq., Badir RA; College of Nursing, Al-Bayan University, Baghdad, Iraq., Almalki SG; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Majmaah, 11952, Saudi Arabia., Tayyib NA; Vice Deanship, Postgraduate Research and Scientific Studies, Faculty of Nursing, Umm Al-Qura University, Makkah, Saudi Arabia., Shahab S; Department of Business Administration, College of Business Administration, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia., Romero-Parra RM; Department of General Studies, Universidad Continental. Lima, Universidad Continental, Lima, Peru., Abid MK; Department of Anesthesia, College of Health & medical Technology, Al-Ayen University, Thi-Qar, Iraq., Hussien BM; Medical Laboratory Technology Department, College of Medical Technology, The Islamic University, Najaf, Iraq., Ramaiah P; Faculty of Nursing, Umm al- Qura University, Makkah, Saudi Arabia.
Jazyk: angličtina
Zdroj: BMC endocrine disorders [BMC Endocr Disord] 2023 Oct 20; Vol. 23 (1), pp. 227. Date of Electronic Publication: 2023 Oct 20.
DOI: 10.1186/s12902-023-01477-1
Abstrakt: Background: Recent studies have revealed some conflicting results about the health effects of caffeine. These studies are inconsistent in terms of design and population and source of consumed caffeine. In the current study, we aimed to evaluate the possible health effects of dietary caffeine intake among overweight and obese individuals.
Methods: In this cross-sectional study, 488 apparently healthy individuals with overweight and obesity were participated. Dietary intake was assessed by a Food Frequency Questionnaire (FFQ) and the amount of dietary caffeine was calculated. Body composition was determined by bioelectrical impedance analysis (BIA). Enzymatic methods were used to evaluate serum lipid, glucose, and insulin concentrations.
Results: Those at the highest tertile of dietary caffeine intake had lower percentage of fat mass, higher fat free mass and appetite score (P < 0.05). Also, lower total cholesterol (TC) and low density lipoprotein cholesterol (LDL-c) was observed in higher tertiles of dietary caffeine intake compared with lower tertiles. In multinomial adjusted models, those at the second tertile of dietary caffeine intake were more likely to have higher serum insulin (P = 0.04) and lower homeostatic model assessment of insulin resistance (HOMA-IR) values compared with first tertile (P = 0.03) in crude model. While, in the age, body mass index (BMI), sex, physical activity, socio-economic status (SES) and energy intake -adjusted model (Model III), those at the third tertile of dietary caffeine intake were more likely to have low serum LDL concentrations [odds ratio (OR) = 0.957; CI = 0.918-0.997; P = 0.04]. With further adjustment to dietary vegetable, fiber and grain intake, those at the third tertile of dietary caffeine intake were more likely to have low systolic blood pressure (SBP), LDL and high HDL levels compared with those at the first tertile (P < 0.05).
Conclusion: High intakes of dietary caffeine was associated with lower LDL, SBP, insulin resistance and higher HDL concentrations among overweight and obese individuals. However, due to observational design of the study, causal inference is impossible and further studies are warranted to confirm our findings.
(© 2023. BioMed Central Ltd., part of Springer Nature.)
Databáze: MEDLINE
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