Non-digestible oligosaccharides-based prebiotics to ameliorate obesity: Overview of experimental evidence and future perspectives.

Autor: Divyashri G; Department of Biotechnology, M S Ramaiah Institute of Technology, Bengaluru, 560 054 India., Karthik P; Department of Food Technology, Faculty of Engineering, Karpagam Academy of Higher Education, Coimbatore, 641 021 India., Murthy TPK; Department of Biotechnology, M S Ramaiah Institute of Technology, Bengaluru, 560 054 India., Priyadarshini D; Department of Biotechnology, M S Ramaiah Institute of Technology, Bengaluru, 560 054 India., Reddy KR; School of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW 2006 Australia., Raghu AV; Faculty of Allied Health Sciences, BLDE (Deemed-to-Be University), Vijayapura, 586103 Karnataka India., Vaidyanathan VK; Department of Biotechnology, School of Bioengineering, Integrated Bioprocessing Laboratory, SRM Institute of Science and Technology (SRM IST), 603 203 Kattankulathur, India.
Jazyk: angličtina
Zdroj: Food science and biotechnology [Food Sci Biotechnol] 2023 Aug 09; Vol. 32 (14), pp. 1993-2011. Date of Electronic Publication: 2023 Aug 09 (Print Publication: 2023).
DOI: 10.1007/s10068-023-01381-3
Abstrakt: The diverse populations reportedly suffer from obesity on a global scale, and inconclusive evidence has indicated that both environmental and genetic factors are associated with obesity development. Therefore, a need exists to examine potential therapeutic or prophylactic molecules for obesity treatment. Prebiotics with non-digestible oligosaccharides (NDOs) have the potential to treat obesity. A limited number of prebiotic NDOs have demonstrated their ability as a convincing therapeutic solution to encounter obesity through various mechanisms, viz .,  stimulating beneficial microorganisms, reducing the population of pathogenic microorganisms, and also improving lipid metabolism and glucose homeostasis. NDOs include pectic-oligosaccharides, fructo-oligosaccharides, xylo-oligosaccharides, isomalto-oligosaccharides, manno-oligosaccharides and other oligosaccharides which significantly influence the overall human health by different mechanisms. This review provides the treatment of obesity benefits by incorporating these prebiotic NDOs, according to established scientific research, which shows their good effects extend beyond the colon.
Competing Interests: Conflict of interestThe authors declare no competing interests.
(© The Korean Society of Food Science and Technology 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
Databáze: MEDLINE
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