Comparison of inpatient psychiatric medication management in gender diverse youth with cisgender peers.

Autor: Carrillo N; PGY2 Psychiatric Pharmacy Resident, University of Kansas Health System, Kansas City, Kansas., McGurran M; Advanced Practice Pharmacist-Psychiatry, University of Kansas Health System, Kansas City, Kansas., Melton BL; Associate Professor, Pharmacy Practice, University of Kansas School of Pharmacy, Lawrence, Kansas., Moeller KE; PGY2 Psychiatric Pharmacy Resident, University of Kansas Health System, Kansas City, Kansas.; Advanced Practice Pharmacist-Psychiatry, University of Kansas Health System, Kansas City, Kansas.; Associate Professor, Pharmacy Practice, University of Kansas School of Pharmacy, Lawrence, Kansas.
Jazyk: angličtina
Zdroj: The mental health clinician [Ment Health Clin] 2023 Aug 07; Vol. 13 (4), pp. 169-175. Date of Electronic Publication: 2023 Aug 07 (Print Publication: 2023).
DOI: 10.9740/mhc.2023.08.169
Abstrakt: Introduction: The primary objective was to determine if gender diverse (GD) youth receive different psychotropic prescribing compared with cisgender (CG) peers with the same diagnosis. Secondary objectives include evaluation of readmission rates and the effect of gender-affirming hormone therapy (GAHT) on psychiatric outcomes in transgender (TG) patients.
Methods: A total of 255 GD youth patients were retrospectively matched to CG controls based on age, primary discharge diagnosis, and year of admission. Data collection included psychotropic medications at admission and discharge, baseline demographics, time to readmission, and total number of readmissions within 6 months. Use of GAHT was also documented. Wilcoxon signed rank test was used for continuous and χ 2 for nominal data with an a priori α of 0.05.
Results: MDD was the primary discharge diagnosis in 74% of patients. GD youth were more likely to present on antidepressants ( P  = .031) and antipsychotics ( P  = .007), and to be discharged with antipsychotics ( P  = .003). They were additionally more likely to be readmitted within 30 days of discharge ( P  = .032). TG youth on GAHT (13%) had fewer readmissions ( P  = .046) than those not on GAHT, but there were no differences in psychotropic prescribing.
Discussion: Higher antipsychotic and antidepressant prescribing were seen in the GD population despite the same mental health diagnosis. Despite higher prescribing in the GD population, patients presented for readmission within 30 days more frequently, which may represent a need for more rigorous transitions-of-care practices in this population.
Competing Interests: Disclosures: None of the investigators have any real or perceived conflicts of interest pertaining to this research to disclose. Funding was not required, requested, nor accepted in the course of this research.
(© 2023 AAPP. The Mental Health Clinician is a publication of the American Association of Psychiatric Pharmacists.)
Databáze: MEDLINE