Surgery or Not? A Systematic Review of Facial Congenital Melanocytic Nevi Treatment Patterns and Outcomes.

Autor: Ibelli TJ, Bauer B; Department of Plastic and Reconstructive Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL., Kleinman EP; From the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Kuruvilla A; Division of Plastic and Reconstructive Surgery, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY., Mendiratta D; Division of Plastic and Reconstructive Surgery, Rutgers New Jersey Medical School, Newark, NJ., Scope A, Seyidova N; Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, NY., Taub PJ; Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.
Jazyk: angličtina
Zdroj: Annals of plastic surgery [Ann Plast Surg] 2024 Jan 01; Vol. 92 (1), pp. 120-132. Date of Electronic Publication: 2023 Sep 11.
DOI: 10.1097/SAP.0000000000003676
Abstrakt: Background: Treatment management for congenital melanocytic nevi (CMN) on the face (FCMN) is highly variable and requires a thorough assessment of multiple factors. To date, a systematic review of FCMN treatment is lacking. The purpose of the present study was to elucidate the frequency, variety, and outcomes of treatment modalities for FCMN with different levels of complexity.
Methods: A comprehensive review of Pubmed, Embase, and Google Scholar databases from 1950 to 2022 was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Articles reporting on FCMN treatment approaches, outcomes, and associated complications were screened and data were extracted according to inclusion criteria. Data were tabulated for thematic analysis of FCMN treatment types, anatomic locations, outcomes, and complications.
Results: Of the 561 studies retrieved, 34 met inclusion criteria including 19 surgical treatments, 14 nonsurgical treatments, and one combined surgical and nonsurgical treatment study, totaling 356 patients. The majority of treated FCMN were small-to-medium-sized (56%). Facial CMN treated conservatively were mostly located on the cheek (27%) and/or perinasal region (21%), whereas FCMN treated with surgery were primarily located in the periorbital region (44%) and/or the cheek (17%). Across all treatment cohorts, 22% of patients experienced at least one complication, with 12% of complications experienced by patients treated by surgery.
Conclusions: There is a greater need for standardized FCMN nomenclature that encompasses nevi pattern, dimensions, anatomical coverage, and quantitative measurements of treatment outcome. Future studies should focus on identifying anatomic locations of FCMN that are more prone to complications and determine which treatment approach optimizes outcomes.
Competing Interests: Sources of funding and conflicts of interest: none declared.
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Databáze: MEDLINE