Synergistic metabolism of salivary MUC5B in oral commensal bacteria during early biofilm formation.

Autor: Robertsson C; Department of Oral Biology, Faculty of Odontology and Biofilms Research Center for Biointerfaces, Malmö University , Malmö, Sweden., Svensäter G; Department of Oral Biology, Faculty of Odontology and Biofilms Research Center for Biointerfaces, Malmö University , Malmö, Sweden., Davies JR; Department of Oral Biology, Faculty of Odontology and Biofilms Research Center for Biointerfaces, Malmö University , Malmö, Sweden., Bay Nord A; Swedish NMR Centre, Gothenburg University , Gothenburg, Sweden., Malmodin D; Swedish NMR Centre, Gothenburg University , Gothenburg, Sweden., Wickström C; Department of Oral Biology, Faculty of Odontology and Biofilms Research Center for Biointerfaces, Malmö University , Malmö, Sweden.
Jazyk: angličtina
Zdroj: Microbiology spectrum [Microbiol Spectr] 2023 Dec 12; Vol. 11 (6), pp. e0270423. Date of Electronic Publication: 2023 Oct 19.
DOI: 10.1128/spectrum.02704-23
Abstrakt: Importance: The study of bacterial interactions and salivary-mediated regulation of early dental biofilm activity is of interest for understanding oral microbial adaptation to environmental cues and biofilm maturation. Findings in oral commensals can prove useful from the perspectives of both oral and systemic health of the host, as well as the understanding of general microbial biofilm physiology. The knowledge may provide a basis for the development of prognostic biomarkers, or development of new treatment strategies, related to oral health and disease and possibly also to other biofilm-induced conditions. The study is also an important step toward developing the methodology for similar studies in other species and/or growth conditions.
Competing Interests: The authors declare no conflict of interest.
Databáze: MEDLINE