Seroprevalence of SARS-CoV-2 in Niger State: Pilot Cross-Sectional Study.

Autor:	Majiya H; Department of Microbiology, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Trans-Saharan Disease Research Center, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Aliyu-Paiko M; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Trans-Saharan Disease Research Center, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Biochemistry, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Balogu VT; Department of Microbiology, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Musa DA; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Trans-Saharan Disease Research Center, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Biochemistry, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Salihu IM; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Biology, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Kawu AA; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Trans-Saharan Disease Research Center, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Computer Science, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Bashir IY; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Geography, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Sani AR; Department of Microbiology, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Trans-Saharan Disease Research Center, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Baba J; Department of Microbiology, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Muhammad AT; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Mathematics, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Jibril FL; Department of Microbiology, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Bala E; Department of Microbiology, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Obaje NG; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Aliyu YB; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Mathematics, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Muhammad RG; Department of Microbiology, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Mohammed H; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Biochemistry, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Gimba UN; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Biology, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Uthman A; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Biochemistry, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Liman HM; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Geography, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Alhaji SA; General Hospital, Minna, Nigeria., James JK; Niger State Ministry of Health, Minna, Nigeria., Makusidi MM; Niger State Ministry of Health, Minna, Nigeria., Isah MD; General Hospital, Minna, Nigeria., Abdullahi I; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Computer Science, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Ndagi U; Trans-Saharan Disease Research Center, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; General Hospital, Minna, Nigeria.; Ibrahim Badamasi Babangida Specialised Hospital, Minna, Nigeria., Waziri B; Ibrahim Badamasi Babangida Specialised Hospital, Minna, Nigeria., Bisallah CI; Department of Microbiology, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Dadi-Mamud NJ; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Biology, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Ibrahim K; Department of Microbiology, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria., Adamu AK; Center for Applied Sciences and Technology Research, Ibrahim Badamasi Babangida University, Lapai, Nigeria.; Department of Biology, Ibrahim Badamasi Babangida University, Lapai, Nigeria.
Jazyk:	angličtina
Zdroj:	JMIRx med [JMIRx Med] 2023 Oct 17; Vol. 4, pp. e29587. Date of Electronic Publication: 2023 Oct 17.
DOI:	10.2196/29587
Abstrakt:	Background: The COVID-19 pandemic caused by SARS-CoV-2 is causing ongoing human and socioeconomic losses. Objective: To know how far the virus has spread in Niger State, Nigeria, a pilot study was carried out to determine the SARS-CoV-2 seroprevalence, patterns, dynamics, and risk factors in the state. Methods: A cross-sectional study design and clustered, stratified random sampling strategy were used to select 185 test participants across the state. SARS-CoV-2 IgG and IgM rapid test kits (colloidal gold immunochromatography lateral flow system) were used to determine the presence or absence of antibodies to the virus in the blood of sampled participants across Niger State from June 26 to 30, 2020. The test kits were validated using the blood samples of some of the Nigeria Center for Disease Control-confirmed positive and negative COVID-19 cases in the state. SARS-CoV-2 IgG and IgM test results were entered into the Epi Info questionnaire administered simultaneously with each test. Epi Info was then used to calculate the arithmetic mean and percentage, odds ratio, χ2 statistic, and regression at a 95% CI of the data generated. Results: The seroprevalence of SARS-CoV-2 in Niger State was found to be 25.4% (47/185) and 2.2% (4/185) for the positive IgG and IgM results, respectively. Seroprevalence among age groups, genders, and occupations varied widely. The COVID-19 asymptomatic rate in the state was found to be 46.8% (22/47). The risk analyses showed that the chances of infection are almost the same for both urban and rural dwellers in the state. However, health care workers, those who experienced flulike symptoms, and those who had contact with a person who traveled out of Nigeria in the last 6 months (February to June 2020) were at double the risk of being infected with the virus. More than half (101/185, 54.6%) of the participants in this study did not practice social distancing at any time since the pandemic started. Participants' knowledge, attitudes, and practices regarding COVID-19 are also discussed. Conclusions: The observed Niger State SARS-CoV-2 seroprevalence and infection patterns meansuggest that the virus has widely spread, far more SARS-CoV-2 infections have occurred than the reported cases, and there is a high asymptomatic COVID-19 rate across the state. (© Hussaini Majiya, Mohammed Aliyu-Paiko, Vincent Tochukwu Balogu, Dickson Achimugu Musa, Ibrahim Maikudi Salihu, Abdullahi Abubakar Kawu, Ishaku Yakubu Bashir, Aishat Rabiu Sani, John Baba, Amina Tako Muhammad, Fatimah Ladidi Jibril, Ezekiel Bala, Nuhu George Obaje, Yahaya Badeggi Aliyu, Ramatu Gogo Muhammad, Hadiza Mohammed, Usman Naji Gimba, Abduljelili Uthman, Hadiza Muhammad Liman, Sule Alfa Alhaji, Joseph Kolo James, Muhammad Muhammad Makusidi, Mohammed Danasabe Isah, Ibrahim Abdullahi, Umar Ndagi, Bala Waziri, Chindo Ibrahim Bisallah, Naomi John Dadi-Mamud, Kolo Ibrahim, Abu Kasim Adamu. Originally published in JMIRx Med (https://med.jmirx.org).)
Databáze:	MEDLINE
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