Calcifications in oral carcinomas: Depicts diversity of calcium in cancer biology!

Autor: Banerjee A; Department of Oral and Maxillofacial Pathology, Awadh Dental College and Hospital, Jamshedpur, Jharkhand, India., Nandini DB; Department of Oral Pathology and Microbiology, Dental College, Regional Institute of Medical Sciences Imphal, Manipur, India., Misra SR; Department of Oral Medicine and Radiology, Institute of Dental Sciences, Siksha 'O' Anusandhan University, Bhubaneswar, Odisha, India., Chakraborty B; Department of Oral and Maxillofacial Pathology, Burdwan Dental College, Bardhaman, West Bengal, India.
Jazyk: angličtina
Zdroj: Journal of oral and maxillofacial pathology : JOMFP [J Oral Maxillofac Pathol] 2023 Apr-Jun; Vol. 27 (2), pp. 396-398. Date of Electronic Publication: 2023 Jul 13.
DOI: 10.4103/jomfp.jomfp_313_22
Abstrakt: Calcifications in the soft tissues can be accidental findings during diagnostic procedures. Oral squamous cell carcinoma (OSCC) forms the major percentage of oral malignancies; calcifications are rare findings in OSCC. Calcifications are seen as a result of necrosis, chronic inflammations as well as degenerative changes and imbalances of the local calcium and phosphorous environment. The presence of calcifications can be a prognostic marker, hypothesizing that the influx of calcium from hard tissues into the soft tissues, can probably determine the invasive nature and the destructive characteristics of the carcinoma; hence, detecting calcifications can help us in predicting the prognosis and spread of the malignancy.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2023 Journal of Oral and Maxillofacial Pathology.)
Databáze: MEDLINE