The Evaluation of Different Treatment Approaches in Patients With Earthquake-Related Crush Syndrome.

Autor:	Koyuncu S; Nephrology, Kayseri State Hospital, Kayseri, TUR., Sipahioglu H; Internal Medicine, Kayseri City Training and Research Hospital, Kayseri, TUR., Bol O; Emergency Medicine, University of Health Sciences, Kayseri City Hospital, Kayseri, TUR., İlik HKZ; Internal Medicine, Kayseri City Hospital, Kayseri, TUR., Dilci A; Internal Medicine, Kayseri City Hospital, Kayseri, TUR., Elmaağaç M; Internal Medicine, Kayseri City Hospital, Kayseri, TUR., Yalçınkaya M; Internal Medicine, Kayseri City Hospital, Kayseri, TUR., Gencer V; Internal Medicine, Kayseri City Hospital, Kayseri, TUR., Ozan F; Orthopaedics, Kayseri City Hospital, Kayseri, TUR., Günal Aİ; Nephrology, Erciyes Universty, Kayseri, TUR., Kocyigit I; Nephrology, Erciyes University, Kayseri, TUR.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Oct 17; Vol. 15 (10), pp. e47194. Date of Electronic Publication: 2023 Oct 17 (Print Publication: 2023).
DOI:	10.7759/cureus.47194
Abstrakt:	Background: On February 6, 2023, an earthquake occurred in Kahramanmaras, Turkey, resulting in loss of life, injuries, and the displacement of thousands of people. The aim of this study is to determine the factors affecting amputation and fasciotomy decisions in patients with crush syndrome, along with clinical laboratory parameters. Materials and Methods: The study included patients over 18 years of age who presented with crush injuries and exhibited systemic symptoms. Inclusion criteria comprised patients with creatine kinase (CK) levels exceeding 1,000 IU/L, oliguria (urine output less than 400 mL per day), elevated blood urea nitrogen (BUN) levels surpassing 40 mg/dL, serum creatinine exceeding 1.5 mg/dL, potassium levels over 6 mEq/L, phosphorus levels surpassing 8 mg/dL, and serum calcium levels below 8 mg/dL. Multiple parameters were evaluated, including blood glucose, serum sodium, potassium, calcium, phosphorus, BUN, creatinine, uric acid, CK, albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, direct bilirubin, prothrombin time (international normalized ratio (INR)), urinalysis, C-reactive protein (CRP), venous blood gas, ECG, and chest radiography. Results: Following the Maraş earthquake, a total of 3,184 patients were admitted to our hospital within the first seven days. Out of these patients, 2,216 received outpatient treatment, 639 were hospitalized in the general ward, and 128 were admitted to the intensive care unit. Among the admitted patients, 237 were diagnosed with crush syndrome, with 126 being male and 111 being female. The average duration of being trapped under debris was eight hours, ranging from four to 36 hours. In the study population, extremity trauma was observed in 84 patients, thoracic trauma in 32 patients, and abdominal trauma in 20 patients. Erythrocyte replacement was administered to 123 patients, while fresh frozen plasma was given to 69 patients, for a total of 1008 units utilized. Mannitol infusions were provided to 58 patients, while bicarbonate infusions were administered to 116 patients. Among the cohort, 71 patients underwent dialysis, with nine of them receiving hemodialysis along with mannitol. Additionally, 67 patients experienced stage 3 acute kidney injury, and 41 patients were deceased. None of the patients required permanent hemodialysis. Conclusion: Earthquakes are considered to be one of nature's most significant and inevitable disasters. While it is impossible to prevent them, effective management strategies are crucial in mitigating the ensuing chaos and reducing casualties. In order to achieve this, it is imperative to draw lessons from past seismic events and apply appropriate treatment protocols to the affected individuals. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Koyuncu et al.)
Databáze:	MEDLINE
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