Celochalcoside, a new quinochalcone C -glycoside from Celosia trigyna .

Autor: El-Desouky SK; Chemistry Department, Faculty of Science, Jazan University, Jazan 2097, Kingdom of Saudi Arabia.; Phytochemistry and Plant Systematic Department, National Research Centre, Dokki, Cairo 12311, Egypt.
Jazyk: angličtina
Zdroj: Journal of Asian natural products research [J Asian Nat Prod Res] 2024 May; Vol. 26 (5), pp. 644-651. Date of Electronic Publication: 2023 Oct 16.
DOI: 10.1080/10286020.2023.2269528
Abstrakt: A new quinochalcone C -glycoside featuring a unique quinonoid moiety, named celochalcoside ( 1 ), was isolated from the n -butanol extract of the aerial parts of Celosia trigyna L. The structure was determined by extensive spectroscopic analysis as well as mass spectrometric data. Compound 1 showed moderate cytotoxic activities against breast cancer cell lines (MCF-7), colon cancer cell lines (HT-29) and hepatocellular carcinoma cell lines (HepG2) with IC 50 values of 23.16, 37.05 and 18.35 μg/ml, respectively.
Databáze: MEDLINE