Sexual Health Assessment in Women with Lung Cancer study: Sexual health assessment in women with lung cancer.

Autor: Florez N; Harvard Medical School, Boston, Massachusetts, USA.; Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Kiel L; Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Meza K; Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Wei Z; Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Mazzola E; Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Velazquez AI; UCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA., Franco I; Harvard Medical School, Boston, Massachusetts, USA.; Dana-Farber Cancer Institute, Boston, Massachusetts, USA.; Brigham and Women's Hospital, Boston, Massachusetts, USA., Fidler MJ; Rush University Medical Center, Chicago, Illinois, USA., Elkins I; EGFR Resisters, Chicago, Illinois, USA., Feldman J; EGFR Resisters, Chicago, Illinois, USA., Seaborne L; University of Wisconsin, Madison, Wisconsin, USA., Heisler C; University of Wisconsin, Madison, Wisconsin, USA., King JC; GO2 for Lung Cancer, Washington, District of Columbia, USA., Moore A; LUNGevity Foundation for Lung Cancer, Bethesda, Maryland, USA., Wiens J; Merck Pharmaceuticals, Rahway, New Jersey, USA., Kushner D; University of Wisconsin, Madison, Wisconsin, USA.
Jazyk: angličtina
Zdroj: Cancer [Cancer] 2024 Feb 01; Vol. 130 (3), pp. 375-384. Date of Electronic Publication: 2023 Oct 16.
DOI: 10.1002/cncr.35057
Abstrakt: Background: Sexual health is understudied and underreported in patients with lung cancer, and most data precede the approval of widely used targeted therapies and immune checkpoint inhibitors. The authors sought to evaluate the prevalence of sexual dysfunction in women with lung cancer in our current clinical environment.
Methods: This cross-sectional survey study was administered online to 249 women via the GO2 for Lung Cancer (GO2) Registry, using the Patient-Reported Outcomes Measurement Information System Sexual Function and Satisfaction Measures questionnaire. Participants were recruited between June 2020 to June 2021. Eligibility criteria included age >18 years, self-identifying as a woman, fluency in English, and a lung cancer diagnosis within 10 years.
Results: Most (67%) had stage IV lung cancer and 47% were receiving targeted therapy; 66% were undergoing active treatment. Despite 54% of participants reporting "recent" sexual activity, most (77%) indicated having little to no interest in sexual activity and 48% reported recent minimal satisfaction with their sex life. The most common reasons negatively affecting participants' satisfaction with their sex life included fatigue (40%) and feeling sad/unhappy (28%). Common reasons for lack of recent sexual activity included lack of interest (68%) and vaginal dryness or pain (30%). Compared to pre-diagnosis, women were significantly less likely to have recent interest in sexual activity. In multivariable logistic-regression, vaginal dryness showed a significant negative association with recent interest in sexual activity.
Conclusions: Sexual dysfunction is prevalent in women with lung cancer. Sexual health should be integrated into routine care for patients with lung cancer.
(© 2023 American Cancer Society.)
Databáze: MEDLINE
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