Beyond Attention-Deficit Hyperactivity Disorder: Exploring Psychiatric Comorbidities and Their Neuropsychological Consequences in Adults.

Autor: Roh HJ; Department of Psychiatry, Nowon Eulji University Hospital, Eulji University School of Medicine, Seoul, Korea., Bahn GH; Department of Psychiatry, Kyung Hee University School of Medicine, Seoul, Korea., Lee SY; Leemind Psychiatric Clinic, Seoul, Korea., Joung YS; Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Kim B; Department of Psychiatry, Inje University College of Medicine, Seoul, Korea., Kim EJ; Department of Psychiatry, College of Medicine, Ewha Womans University, Seoul, Korea., Lee SI; Department of Psychiatry, Soonchunhyang University College of Medicine, Bucheon, Korea., Hong M; Department of Psychiatry, Myongji Hospital, Hanyang University College of Medicine, Goyang, Korea., Han DH; Department of Psychiatry, Chung-Ang University College of Medicine, Seoul, Korea., Lee YS; Department of Psychiatry, Chung-Ang University College of Medicine, Seoul, Korea., Yoo HK; Department of Clinical Psychiatry, Seoul Brain Research Institute, Seoul, Korea., Bhang SY; Department of Psychiatry, Nowon Eulji University Hospital, Eulji University School of Medicine, Seoul, Korea.; Nowon Community Addiction Management Center, Seoul, Korea.; Eulji Psychiatry and Medical Science Center, Seoul, Korea.
Jazyk: angličtina
Zdroj: Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry [Soa Chongsonyon Chongsin Uihak] 2023 Oct 01; Vol. 34 (4), pp. 275-282.
DOI: 10.5765/jkacap.230050
Abstrakt: Objectives: This study aimed to identify the psychiatric comorbidity status of adult patients diagnosed with attention-deficit hyperactivity disorder (ADHD) and determine the impact of comorbidities on neuropsychological outcomes in ADHD.
Methods: The study participants were 124 adult patients with ADHD. Clinical psychiatric assessments were performed by two boardcertified psychiatrists in accordance with the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. All participants were assessed using the Mini-International Neuropsychiatric Interview Plus version 5.0.0 to evaluate comorbidities. After screening, neuropsychological outcomes were assessed using the Comprehensive Attention Test (CAT) and the Korean version of the Wechsler Adult Intelligence Scale, Fourth Edition (K-WAIS-IV).
Results: Mood disorders (38.7%) were the most common comorbidity of ADHD, followed by anxiety (18.5%) and substance use disorders (13.7%). The ADHD with comorbidities group showed worse results on the Perceptual Organization Index and Working Memory Index sections of the K-WAIS than the ADHD-alone group (p=0.015 and p=0.024, respectively). In addition, the presence of comorbidities was associated with worse performance on simple visual commission errors in the CAT tests (p=0.024).
Conclusion: These findings suggest that psychiatric comorbidities are associated with poor neuropsychological outcomes in adult patients with ADHD, highlighting the need to identify comorbidities in these patients.
Competing Interests: Conflicts of Interest Geon Ho Bahn and Minha Hong, a contributing editor of the Journal of the Korean Academy of Child and Adolescent Psychiatry, were not involved in the editorial evaluation or decision to publish this article. All remaining authors have declared no conflicts of interest.
(Copyright © 2023 Korean Academy of Child and Adolescent Psychiatry.)
Databáze: MEDLINE