Case report: isolation of Hydrogenophaga from septic blood culture following near-death drowning in lakewater.

Autor:	Feichtinger S; Department of Anesthesiology, Division of Critical Care, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Lazar AA; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA., Luebbe MA; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA., Accola MA; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA., Jung-Hynes BD; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA., Anderson PJ; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA., Koglin KM; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA., Schliesman KS; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA., Ehlenbach W; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Smith J; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Chen DJ; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Rehrauer WM; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Bailey AL; University of Wisconsin Hospitals and Clinics, Clinical Laboratories, Madison, WI, USA.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Jazyk:	angličtina
Zdroj:	Access microbiology [Access Microbiol] 2023 Sep 19; Vol. 5 (9). Date of Electronic Publication: 2023 Sep 19 (Print Publication: 2023).
DOI:	10.1099/acmi.0.000533.v4
Abstrakt:	A patient suffered a non-fatal wet drowning in a freshwater lake and developed bacteraemia several days later. Blood culture grew a Gram-negative rod that could not be identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). 16S ribosomal RNA sequencing of the isolate identified the microbe as Hydrogenophaga laconesensis - an environmental microbe commonly found in freshwater. The recovery of multiple pathogenic micro-organisms (although not H. laconesensis ) from culture of respiratory specimens prompted the initiation of antibiotic therapy with cefepime and, later, vancomycin. The patient's clinical course gradually improved over the course of 2 weeks and she was ultimately discharged home with minimal sequelae. To our knowledge, this is the first evidence of human infection with bacteria in the genus Hydrogenophaga . Hydrogenophaga may be considered in cases of freshwater near-drowning, and MALDI-TOF MS databases should be updated to include H. laconesensis . Competing Interests: The authors declare that there are no conflicts of interest. (© 2023 The Authors.)
Databáze:	MEDLINE
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