Secondary somatic glioblastoma arising from a mature ovarian cystic teratoma in a patient with underlying Li-Fraumeni syndrome.

Autor:	Bussies PL; Women's Health Institute, Cleveland Clinic Foundation, Cleveland, OH, United States., Chau DB; Women's Health Institute, Cleveland Clinic Foundation, Cleveland, OH, United States., Hunt JT; Women's Health Institute, Cleveland Clinic Foundation, Cleveland, OH, United States., Policarpio-Nicolas MLC; Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH, United States., Friedman C; Genomic Medicine Institute, Cleveland Clinic Foundation, Cleveland, OH, United States., McKenney JK; Genomic Medicine Institute, Cleveland Clinic Foundation, Cleveland, OH, United States., Yeaney GA; Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH, United States., Peereboom DM; Brain Tumor and Neuro-Oncology Center, Cleveland Clinic Foundation, Cleveland, OH, United States., Beffa L; Women's Health Institute, Cleveland Clinic Foundation, Cleveland, OH, United States.
Jazyk:	angličtina
Zdroj:	Gynecologic oncology reports [Gynecol Oncol Rep] 2023 Sep 26; Vol. 49, pp. 101279. Date of Electronic Publication: 2023 Sep 26 (Print Publication: 2023).
DOI:	10.1016/j.gore.2023.101279
Abstrakt:	•First report of a secondary somatic glioblastoma arising from MCT-MT in a patient with underlying Li-Fraumeni syndrome.•The rarity of glioblastoma arising from MCT-MT warrants investigation for underlying genetic predisposition.•Glioblastomas arising from MCT-MT appear to exhibit wild type IDH gene status.•Advanced-stage glioblastoma arising from MCT-MT exhibits aggressive behavior and requires adjuvant therapy.•Optimal adjuvant therapy regimen for glioblastoma arising from MCT-MT remains unknown. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2023 Published by Elsevier Inc.)
Databáze:	MEDLINE
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