| Autor: |
Babunashvili EL; Gynecological Department of the Moscow Regional Research Institute of Obstetrics and Gynecology, State-Funded Health Care Facility of Moscow Region (GBUZ MO MONIIAG), 22A Pokrovka, 101000 Moscow, Russia., Son DY; Gynecological Department of the Moscow Regional Research Institute of Obstetrics and Gynecology, State-Funded Health Care Facility of Moscow Region (GBUZ MO MONIIAG), 22A Pokrovka, 101000 Moscow, Russia., Buyanova SN; Gynecological Department of the Moscow Regional Research Institute of Obstetrics and Gynecology, State-Funded Health Care Facility of Moscow Region (GBUZ MO MONIIAG), 22A Pokrovka, 101000 Moscow, Russia., Schukina NA; Gynecological Department of the Moscow Regional Research Institute of Obstetrics and Gynecology, State-Funded Health Care Facility of Moscow Region (GBUZ MO MONIIAG), 22A Pokrovka, 101000 Moscow, Russia., Popov AA; Gynecological Department of the Moscow Regional Research Institute of Obstetrics and Gynecology, State-Funded Health Care Facility of Moscow Region (GBUZ MO MONIIAG), 22A Pokrovka, 101000 Moscow, Russia., Chechneva MA; Gynecological Department of the Moscow Regional Research Institute of Obstetrics and Gynecology, State-Funded Health Care Facility of Moscow Region (GBUZ MO MONIIAG), 22A Pokrovka, 101000 Moscow, Russia., Glebov TA; Gynecological Department of the Moscow Regional Research Institute of Obstetrics and Gynecology, State-Funded Health Care Facility of Moscow Region (GBUZ MO MONIIAG), 22A Pokrovka, 101000 Moscow, Russia., D'Amato A; Unit of Obstetrics and Gynecology, Department of Biomedical and Human Oncological Science, University of Bari, 70100 Bari, Italy., Haydamous J; Department of Obstetrics and Gynecology, University of Balamand, Beirut 1100, Lebanon., Chiantera V; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90133 Palermo, Italy.; Unit of Gynecologic Oncology, National Cancer Institute-IRCCS-Fondazione 'G. Pascale', 80131 Naples, Italy., Laganà AS; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90133 Palermo, Italy.; Unit of Obstetrics and Gynecology, 'Paolo Giaccone' Hospital, 90127 Palermo, Italy., Etrusco A; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90133 Palermo, Italy.; Unit of Obstetrics and Gynecology, 'Paolo Giaccone' Hospital, 90127 Palermo, Italy. |
| Abstrakt: |
Background : The incidence of pregnant women with uterine fibroids is increasing. As they are reactive to hormonal stimuli, in some cases, uterine fibroids tend to grow during pregnancy and potentially generate symptoms with different levels of severity, causing maternal-fetal complications. In very select cases, when other treatment strategies fail to manage symptoms and there is a substantial risk of adverse pregnancy outcomes, a surgical approach during pregnancy may be considered. Methods : From 2016 to 2021, the data from 28 pregnant women with symptomatic uterine fibroids who underwent laparotomic myomectomy during pregnancy were prospectively collected, and operative and maternal-fetal outcomes were analyzed (ClinicalTrial ID: NCT06009562). Results : The procedure was carried out between 14 and 16 weeks of pregnancy. Four (14.3%) patients had intraoperative complications (miscarriages) and nine (32.1%) had postoperative complications (threatened preterm birth). Overall, 24 (85.7%) women delivered at full term (mean: 38.2 gestational weeks), more than half ( n = 13; 54.2%) by vaginal delivery, with normal fetal weights and 1 and 5 min Apgar scores. Conclusions : Laparotomic myomectomy during pregnancy can be considered in selected cases for uterine fibroids with severe symptoms when other treatment options have failed and there is high risk of adverse maternal-fetal outcomes. |
