Pharmacogenetic Analysis of the Interaction of the Low-Molecular-Weight BDNF Mimetic Dipeptide GSB-106 with TRK Receptors.

Autor: Antipova TA; Zakusov Research Institute of Pharmacology, Moscow, Russia., Logvinov IO; Zakusov Research Institute of Pharmacology, Moscow, Russia., Deyev IE; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia., Povarnina PY; Zakusov Research Institute of Pharmacology, Moscow, Russia., Vakhitova YV; Zakusov Research Institute of Pharmacology, Moscow, Russia., Gudasheva TA; Zakusov Research Institute of Pharmacology, Moscow, Russia. tata-sosnovka@mail.ru., Seredenin SB; Zakusov Research Institute of Pharmacology, Moscow, Russia.
Jazyk: angličtina
Zdroj: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2023 Aug; Vol. 511 (1), pp. 166-168. Date of Electronic Publication: 2023 Oct 13.
DOI: 10.1134/S1607672923700230
Abstrakt: Using TrkA or TrkB receptor gene knockout HT-22 cells, the selectivity of the interaction of the low-molecular-weight dipeptide BDNF mimetic GSB-106 (hexamethylenediamide bis(N-monosuccinyl-L-seryl-L-lysine)) with TrkB receptors was shown.
(© 2023. Pleiades Publishing, Ltd.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje