Septic thrombophlebitis of portal and splenic vein secondary to Fusobacterium nucleatum: A case report of an abdominal variant of lemierre syndrome.

Autor:	Pandey S; Department of Internal Medicine, One Brooklyn Health- Interfaith Medical Center, NY., Rayapureddy AK; Department of Internal Medicine, One Brooklyn Health- Interfaith Medical Center, NY., Manvar K; Department of Hematology and Medical Oncology, One Brooklyn Health- Brookdale University Hospital Medical Center, NY., Edara S; Department of Internal Medicine, One Brooklyn Health- Interfaith Medical Center, NY., Boddu G; Department of Internal Medicine, One Brooklyn Health- Interfaith Medical Center, NY., Thakur A; Department of Internal Medicine, B.P. Koirala Institute of Health Sciences, Dharan, Nepal., Jaswani V; Department of Radiology, One Brooklyn Health- Interfaith Medical Center, NY.
Jazyk:	angličtina
Zdroj:	Medicine [Medicine (Baltimore)] 2023 Oct 13; Vol. 102 (41), pp. e35622.
DOI:	10.1097/MD.0000000000035622
Abstrakt:	Rationale: Septic thrombophlebitis of the internal jugular vein also known as Lemierre syndrome occurs secondary to an oropharyngeal infection often leading to septic embolisms to distant sites. Anaerobic gram-negative bacillus, Fusobacterium nucleatum and Fusobacterium necrophorum are commonly isolated organisms. Fusobacterium species has also been reported to complicate an intra-abdominal infection leading to septic thrombophlebitis of portal vein also known as pylephlebitis or abdominal variant of lemierre syndrome. Patient Concerns: The patient was a middle-aged female patient with chief complaints of abdominal discomfort, intermittent fever and vomiting for one month. Diagnoses: The final diagnosis was septic thrombophlebitis of portal and splenic vein secondary to Fusobacterium nucleatum. Interventions: Patient was managed with broad spectrum intravenous antibiotics with coverage against gram-negative bacilli, anaerobes, and aerobic streptococcus species with therapeutic anticoagulation. Outcomes: Patient gradually improved and was discharged on oral apixaban. She was instructed to follow up with gastrointestinal specialist upon discharge in anticipation of the need for liver transplant in future. Lessons: Due to its high mortality and associated long term disease morbidity, clinicians should always strive towards early diagnosis and treatment of the condition with involvement of multidisciplinary teams. Competing Interests: The authors have no funding and conflicts of interest to disclose. (Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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