Pharmacological potentials of lycopene against aging and aging-related disorders: A review.

Autor: Abir MH; ABEx Bio-Research Center Dhaka Bangladesh.; Faculty of Food Science and Technology Chattogram Veterinary and Animal Sciences University Chattogram Bangladesh., Mahamud AGMSU; ABEx Bio-Research Center Dhaka Bangladesh.; Department of Food Safety and Regulatory Science Chung-Ang University Anseong-si Gyeonggi-do Republic of Korea., Tonny SH; Faculty of Agriculture Bangladesh Agricultural University Mymensingh Bangladesh., Anu MS; Department of Fisheries Biology and Genetics Faculty of Fisheries, Bangladesh Agricultural University Mymensingh Bangladesh., Hossain KHS; Faculty of Agriculture Bangladesh Agricultural University Mymensingh Bangladesh., Protic IA; Department of Plant Pathology Faculty of Agriculture, Bangladesh Agricultural University Mymensingh Bangladesh., Khan MSU; ABEx Bio-Research Center Dhaka Bangladesh.; Department of Crop Botany Faculty of Agriculture, Bangladesh Agricultural University Mymensingh Bangladesh., Baroi A; ABEx Bio-Research Center Dhaka Bangladesh.; Department of Crop Botany Faculty of Agriculture, Bangladesh Agricultural University Mymensingh Bangladesh., Moni A; ABEx Bio-Research Center Dhaka Bangladesh., Uddin MJ; ABEx Bio-Research Center Dhaka Bangladesh.
Jazyk: angličtina
Zdroj: Food science & nutrition [Food Sci Nutr] 2023 Jun 27; Vol. 11 (10), pp. 5701-5735. Date of Electronic Publication: 2023 Jun 27 (Print Publication: 2023).
DOI: 10.1002/fsn3.3523
Abstrakt: Aging and aging-related chronic disorders are one of the principal causes of death worldwide. The prevalence of these disorders is increasing gradually and globally. Considering this unwavering acceleration of the global burden, seeking alternatives to traditional medication to prevent the risk of aging disorders is needed. Among them, lycopene, a carotenoid, is abundant in many fruits and vegetables, including tomatoes, grapefruits, and watermelons, and it has a unique chemical structure to be a potent antioxidant compound. This nutraceutical also possesses several anti-aging actions, including combating aging biomarkers and ameliorating several chronic disorders. However, no systematic evaluation has yet been carried out that can comprehensively elucidate the effectiveness of lycopene in halting the course of aging and the emergence of chronic diseases linked to aging. This review, therefore, incorporates previous pre-clinical, clinical, and epidemiological studies on lycopene to understand its potency in treating aging disorders and its role as a mimic of caloric restriction. Lycopene-rich foods are found to prevent or attenuate aging disorders in various research. Based on the evidence, this review suggests the clinical application of lycopene to improve human health and alleviate the prevalence of aging and aging disorders.
Competing Interests: The authors report no competing interests to declare.
(© 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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