Nanohydroxyapatite in dentistry: A comprehensive review.

Autor:	Pushpalatha C; Department of Pedodontics and Preventive Dentistry, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India., Gayathri VS; Department of Pedodontics and Preventive Dentistry, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India., Sowmya SV; Department of Oral Pathology & Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India., Augustine D; Department of Oral Pathology & Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India., Alamoudi A; Oral Biology Department, King Abdulaziz University, Jeddah, Saudi Arabia., Zidane B; Restorative Dentistry Department, King Abdulaziz University, Jeddah, Saudi Arabia., Hassan Mohammad Albar N; Restorative Department, Jazan University, Jazan, Saudi Arabia., Bhandi S; College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT 84095, USA.
Jazyk:	angličtina
Zdroj:	The Saudi dental journal [Saudi Dent J] 2023 Sep; Vol. 35 (6), pp. 741-752. Date of Electronic Publication: 2023 Jun 07.
DOI:	10.1016/j.sdentj.2023.05.018
Abstrakt:	Enamel, being the hardest and the highest mineralized tissue of the human body, contains nearly 96% inorganic components and 4% organic compounds and water. Dentin contains 65% inorganic components and 35% organic and water content. The translucency and white appearance of enamel are attributed to Hydroxyapatite (HA), which constitutes the major part of the inorganic component of dental hard tissue. With the advent of nanotechnology, the application of Nanohydroxyapatite (nHA) has piqued interest in dentistry due to its excellent mechanical, physical, and chemical properties. Compared to HA, nHA is found to have superior properties such as increased solubility, high surface energy and better biocompatibility. This is due to the morphological and structural similarity of nanosized hydroxyapatite particles to tooth hydroxyapatite crystals. These nanoparticles have been incorporated into various dental formulations for different applications to ensure comprehensive oral healthcare. To prevent dental caries, several nHA based dentifrices, mouth rinsing solutions and remineralizing pastes have been developed. nHA-based materials, such as nanocomposites, nano impression materials, and nanoceramics, have proven to be very effective in restoring tooth deformities (decay, fracture, and tooth loss). The nHA coating on the surface of the dental implant helps it bind to the bone by forming a biomimetic coating. A recent innovative strategy involves using nHA to reduce dentinal hypersensitivity and to reconstruct periodontal bone defects. The purpose of the present review is to discuss the different applications of nHA in dentistry, especially in preventive and restorative dentistry, dental implantology, bleaching and dentine hypersensitivity management. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2023 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.)
Databáze:	MEDLINE
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