MicroRNAs and Diet-induced Weight Loss: What's the Link?
| Autor: | Cannataro R; GalaScreen Laboratories, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy.; Research Division, Dynamical Business & Science Society, DBSS International SAS, 11031 Bogotá, Colombia., Abrego-Guandique DM; Department of Health Sciences, University of Magna Graecia Catanzaro, 88100 Catanzaro, Italy., Caroleo MC; Department of Health Sciences, University of Magna Graecia Catanzaro, 88100 Catanzaro, Italy., Bonilla DA; Research Division, Dynamical Business & Science Society, DBSS International SAS, 11031 Bogotá, Colombia.; Research Group in Biochemistry and Molecular Biology, Universidad Distrital Francisco José de Caldas, 110311 Bogotá, Colombia., Cione E; GalaScreen Laboratories, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. |
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| Jazyk: | angličtina |
| Zdroj: | MicroRNA (Shariqah, United Arab Emirates) [Microrna] 2023; Vol. 12 (3), pp. 205-209. |
| DOI: | 10.2174/0122115366257950230921095548 |
| Abstrakt: | It is now well established that lifestyle, particularly eating habits, modulates the synthesis and action of microRNAs (miRNAs). In particular, several nutritional schemes have proven effective in improving body composition, but molecular mechanisms still need to be fully understood. Within the complex physiological network of food intake regulation, it is essential to understand the changes in endocrine activity after the reduction of adipose tissue during a weight loss program. This could be the key to identifying the optimal endocrine profile in high responders, the assessment of musculoskeletal status, and long-term management. In this review, we summarize the state of the art regarding miRNAs as a function of weight loss and as a mechanistic regulator of the effectiveness of the nutritional program. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.) |
| Databáze: | MEDLINE |
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