Leser-Trélat Syndrome, an Underdiagnosed Cutaneous Paraneoplastic Syndrome That Could Aid in Early Detection of Colon Cancer: A Case Report.
| Autor: | Borja Montes OF; Internal Medicine, University of New Mexico School of Medicine, Albuquerque, USA., Escobar Gil T; Internal Medicine, University of New Mexico School of Medicine, Albuquerque, USA., Cardona Solano C; Internal Medicine, Universidad Libre, Cali, COL., Padilla D; Cardiology, University of New Mexico School of Medicine, Albuquerque, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2023 Sep 08; Vol. 15 (9), pp. e44907. Date of Electronic Publication: 2023 Sep 08 (Print Publication: 2023). |
| DOI: | 10.7759/cureus.44907 |
| Abstrakt: | Leser-Trélat syndrome, a rare cutaneous paraneoplastic phenomenon, has gained attention for its potential role as an early indicator of underlying internal malignancies. This article presents a comprehensive case study of a 67-year-old male with a history of alcohol and tobacco use, emphasizing the importance of recognizing this syndrome in clinical practice. The sudden onset of seborrheic keratoses on the thorax and back, retrospectively identified as Leser-Trélat syndrome, prompted investigations that led to the early diagnosis of a colon adenocarcinoma. We discuss the pathophysiology, clinical relevance, and controversies surrounding this syndrome, highlighting the need for increased awareness among healthcare professionals. Timely recognition of Leser-Trélat syndrome can significantly impact patient care, leading to improved prognoses for associated neoplasms. This case underscores the importance of comprehensive evaluations and further research to enhance our understanding and management of cutaneous paraneoplastic syndromes. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Borja Montes et al.) |
| Databáze: | MEDLINE |
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