Premovement activity in the mesocortical system links peak force but not initiation of force generation under incentive motivation.

Autor:	Sugawara SK; Neural Prosthetics Project, Tokyo Metropolitan Institute of Medical Science, Setagaya, Tokyo 156-8506, Japan.; Section of Brain Function Information, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan.; The Graduate University for Advanced Studies, SOKENDAI, Hayama, Kanagawa 340-0193, Japan., Yamamoto T; Section of Brain Function Information, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan., Nakayama Y; Neural Prosthetics Project, Tokyo Metropolitan Institute of Medical Science, Setagaya, Tokyo 156-8506, Japan., Hamano YH; Section of Brain Function Information, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan., Fukunaga M; Section of Brain Function Information, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan.; The Graduate University for Advanced Studies, SOKENDAI, Hayama, Kanagawa 340-0193, Japan., Sadato N; Section of Brain Function Information, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan.; The Graduate University for Advanced Studies, SOKENDAI, Hayama, Kanagawa 340-0193, Japan.; Research Organization of Science and Technology, Ritsumeikan University, Kusatsu, Shiga 525-8577, Japan., Nishimura Y; Neural Prosthetics Project, Tokyo Metropolitan Institute of Medical Science, Setagaya, Tokyo 156-8506, Japan.
Jazyk:	angličtina
Zdroj:	Cerebral cortex (New York, N.Y. : 1991) [Cereb Cortex] 2023 Nov 27; Vol. 33 (23), pp. 11408-11419.
DOI:	10.1093/cercor/bhad376
Abstrakt:	Motivation facilitates motor performance; however, the neural substrates of the psychological effects on motor performance remain unclear. We conducted a functional magnetic resonance imaging experiment while human subjects performed a ready-set-go task with monetary incentives. Although subjects were only motivated to respond quickly, increasing the incentives improved not only reaction time but also peak grip force. However, the trial-by-trial correlation between reaction time and peak grip force was weak. Extensive areas in the mesocortical system, including the ventral midbrain (VM) and cortical motor-related areas, exhibited motivation-dependent activity in the premovement "Ready" period when the anticipated monetary reward was displayed. This premovement activity in the mesocortical system correlated only with subsequent peak grip force, whereas the activity in motor-related areas alone was associated with subsequent reaction time and peak grip force. These findings suggest that the mesocortical system linking the VM and motor-related regions plays a role in controlling the peak of force generation indirectly associated with incentives but not the initiation of force generation. (© The Author(s) 2023. Published by Oxford University Press.)
Databáze:	MEDLINE
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